ABSTRACT
A behavioral test battery is proposed for wall lizards (Tropidurus oreadicus) that consists of inducing tonic immobility (TI) followed by post-TI behavioral scoring. After the induction of TI, the usual behavioral sequence was flight followed by freezing and tongue-flicking and/or thigmotaxis, with flight being more probable than freezing. These sequences were not observed after restraint in a normal upward position (which induced freezing but not TI) or after handling (which increased the probability of tongue-flicking). Alprazolam and imipramine selectively decreased the duration of TI as well as the following flight and freezing behavior. Tongue-flicking was increased by diazepam and alprazolam, whereas fluoxetine decreased it. Finally, thigmotaxis was reduced by diazepam, alprazolam, and imipramine but increased by fluoxetine. These results suggest that panic and anxiety can be discriminated pharmacologically in wall lizards...