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Rev. Soc. Bras. Med. Trop ; 53: e20190583, 2020. tab, graf
Article in English | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136797

ABSTRACT

Abstract INTRODUCTION: We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak. METHODS: Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018. RESULTS: Of the 605 samples, 167 were CHIKV-positive. Viral isolation was achieved for 20 samples; their phylogenetic analysis (E2 protein) revealed the presence of ECSA lineage and reinforced the phylogenetic relationship between ECSA and Indian Ocean lineages. CONCLUSIONS: The genomic surveillance of CHIKV showed that only ECSA lineage circulated in Bahia since the 2014 outbreak.


Subject(s)
Humans , Male , Female , Adult , Chikungunya virus/genetics , Genome, Viral/genetics , Chikungunya Fever/virology , Phylogeny , Brazil/epidemiology , Disease Outbreaks , Reverse Transcriptase Polymerase Chain Reaction , Epidemiological Monitoring , Chikungunya Fever/epidemiology , Genotype
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