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São Paulo; s.n; 2003. [92] p. ilus, tab.
Thesis in Portuguese | LILACS | ID: lil-408866

ABSTRACT

Desenvolver e caraterizar um modelo animal de retinoblastoma com acometimento vítreo usando células tumorais humanas. Usar, posteriormente este modelo para testes de eficácia da quimioterapia local do retinoblastoma através de injeções peri-oculares de carbopatina. Material e métodos: para desenvolver o modelo doença vítrea /Aims: To develop and charactrize a xenograft model of retinoblastoma with vitreous seeding using human humor cell. And to further use this model to test the efficacy of local chemotherapy of retinoblastoma with peri-ocular injections od carboplatin...


Subject(s)
Animals , Male , Female , Rats , Carboplatin/therapeutic use , Retinoblastoma , Vitreous Body , Chi-Square Distribution , Disease Models, Animal , Ophthalmoscopy , Drug Therapy/adverse effects
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