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Gastroenterol. latinoam ; 22(3): 238-241, jul.-sept. 2011. tab
Article in Spanish | LILACS | ID: lil-661666

ABSTRACT

The epidemiology of liver diseases has been changing over the time, with increasing importance of non-alcoholic fatty liver disease (NAFLD). Objective: To investigate the principal diagnosis of liver diseases in a reference center. Material and Methods: Prospective study of 405 consecutive patients attending theClinica Las Condes Gastroenterology Department, between March and July 2010. Results: 207 (51 percent) were men and 198 (49 percent) women, with a mean age of 54 years old (Range 14-89). From these, 134 (33 percent) had NAFLD, 40 (10 percent) autoimmune hepatitis, 36 (9 percent) primary biliary cirrhosis, 25 (9 percent) chronic hepatitis C, 26 (6,5 percent) Gilbert syndrome, 23 (5,5 percent) acute or chronic hepatitis B, 22 (5 percent) liver transplantation and 87 (65 percent) others diagnosis. From 134 NAFLD cases, 88 (66 percent) were men and 46 (34 percent) women, 72 (54 percent) had overweight, 39 (29 percent) obesity, 100 (75 percent) dyslipidemia and 87 (65 percent) glucose intolerance, insulin resistance and/or diabetes mellitus. Conclusion: NAFLD is currently the main cause of liver disease in a reference center, associated to well known risk factors, increasingly presented in Chile.


La epidemiología de las enfermedades hepáticas ha cambiado a través del tiempo, adquiriendo crecienteimportancia el hígado graso no alcohólico (HGNA). Objetivo: Investigar los principales diagnósticoshepatológicos en un centro de referencia. Material y Método: Estudio prospectivo de 405 pacientes consecutivos ambulatorios, consultantes entre marzo y julio de 2010, al Departamento de Gastroenterología de Clínica Las Condes. Resultados: 207 (51 por ciento) eran hombres y 198 (49 por ciento) mujeres, con edad promedio de 54 años (rango 14-89). De éstos, 134 (33 por ciento) tenían HGNA, 40 (10 por ciento) hepatitis autoinmune, 36 (9 por ciento) cirrosis biliar primaria, 25 (9 por ciento) hepatitis crónica C, 26 (6,5 por ciento) Síndrome de Gilbert, 23 (5,5 por ciento) hepatitis aguda o crónica B, 22 (5 por ciento) trasplante hepático y 89 (22 por ciento) otros diagnósticos. De los 134 casos de HGNA, 88 (66 por ciento) eran hombres y 46 (34 por ciento) mujeres, 72 (54 por ciento) tenían sobrepeso, 39 (29 por ciento) obesidad, 100 (75 por ciento) dislipidemia y 87 (65 por ciento) intolerancia a hidratos de carbono, resistencia a insulina y/o diabetes mellitus. Conclusiones: El HGNA constituye en la actualidad la principal enfermedad hepática en un centro privado en Chile, asociado a factores de riesgo conocidos, cada vez más presentes en nuestro medio.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged, 80 and over , Liver Diseases/epidemiology , Fatty Liver/epidemiology , Liver Cirrhosis, Biliary , Diabetes Mellitus , Dyslipidemias , Gilbert Disease , Prospective Studies , Risk Factors , Hepatitis , Liver Diseases/etiology , Fatty Liver/complications , Obesity , Prevalence , Overweight , Liver Transplantation
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