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Rev. bras. colo-proctol ; 27(3): 322-327, jul.-set. 2007. ilus
Article in Portuguese | LILACS | ID: lil-471020

ABSTRACT

OBJETIVO: Relatar um caso raro de adenocarcinoma de pâncreas que se apresentou como tumores colorretais sincrônicos. Paciente masculino, 76 anos, apresentava dor abdominal difusa de forte intensidade, diarréia e vômitos há sete dias. Tratava de gastrite há dois anos e nos últimos quatro meses apresentava hiporexia e perda de peso. Estava emagrecido, desidratado e desnutrido, com distensão abdominal importante, ruídos hidroaéreos ausentes e dor difusa à palpação abdominal. Exames evidenciaram hiperglicemia, distensão importante do intestino delgado ao raio x, ultra-som de abdome com colecistolitíase e endoscopia digestiva alta com pangastrite, bulboduodenite e papila normal. Tomografia abdominal confirmou colecistolitíase. A colonoscopia mostrou três lesões, em reto médio, cólon transverso e na válvula íleocecal. As biópsias revelaram apenas reação inflamatória. Persistiram os sintomas e decidiu-se submetê-lo a colecistectomia onde foram vistas lesões planas em diafragma cujas biópsias evidenciaram adenocarcinoma. No quinto dia de pós-operatório o paciente apresentava quadro obstrutivo e foi submetido à nova laparotomia com colectomia direita, ileostomia terminal dupla e biópsia pancreática. Esta mostrou adenocarcinoma e o estudo imunoistoquímico positivo para tumor primário do pâncreas. O paciente evoluiu para óbito um mês após. CONCLUSÃO: o exame de imagem normal não descarta a hipótese diagnóstica e quando a origem do tumor primário não está definida é essencial o exame imunoistoquímico para firmar o diagnóstico.


OBJECTIVE: Report a case of a rare pancreatic adenocarcinoma presented as synchronic colorectal tumor. CASE REPORT: Seventy six year old man with high intensity and diffuse abdominal pain, diarrhea and vomiting during seven days. At that moment he had been in treatment for gastritis for 2 years and in the last four months he presented hyporexia and weight loss. He was dehydrated and malnourished, with abdominal distention and diffuse abdominal pain on clinical examination. Laboratorial exams showed hyperglycemia, x-ray revealed intense abdominal distention, abdominal ultrasound revealed cholecystolithiasis and upper digestive endoscopy showed pangastritis. The computed tomography just confirmed the cholecystolithiasis. A colonoscopy was performed and revealed three tumors located in the rectum, transverse colon and ileocecal valve that were biopsed and just showed inflammatory cells. As the symptoms persist he underwent laparoscopic cholecystectomy that was converted to the open technique when it was observed white flat lesions in the diaphragm peritoneum, the biopsies revealed adenocarcinoma. In the fifth postoperatory day the patient developed obstructive symptoms and underwent right colectomy with double terminal colostomy and pancreas biopsy that showed adenocarcinoma with immunohistochemical profile proving the pancreas as the source. The patient died within one month. CONCLUSION: The normal findings in radiological exams do not dismiss a diagnostic hypothesis and when the source of a tumor is not well established the clinical patterns should be considered and the immunohistochemical profile is essential to confirm the diagnosis.


Subject(s)
Humans , Male , Aged , Adenocarcinoma , Colorectal Neoplasms, Hereditary Nonpolyposis , Neoplasm Metastasis , Pancreatic Neoplasms , Tomography, X-Ray Computed
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