ABSTRACT
Abstract Ischemic strokes secondary to occlusion of large vessels have been described in patients with COVID-19. Also, venous thrombosis and pulmonary thromboembolism have been related to the disease. Vascular occlusion may be associated with a prothrombotic state due to COVID-19-related coagulopathy and endotheliopathy. Intracranial hemorrhagic lesions can additionally be seen in these patients. The causative mechanism of hemorrhage could be associated with anticoagulant therapy or factors such as coagulopathy and endotheliopathy. We report on cases of ischemic, thrombotic, and hemorrhagic complications in six patients diagnosed with SARS-CoV-2 infection. Chest computed tomography (CT) showed typical SARS-CoV-2 pneumonia findings in all the cases, which were all confirmed by either serology or reverse transcription polymerase chain reaction (RT-PCR) tests.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Thromboembolism/complications , COVID-19/complications , Diagnostic Imaging/methods , Ischemic Stroke , HemorrhageABSTRACT
Abstract Background Lung ultrasound (LUS) can detect interstitial alveolar changes confined to the subpleural region, like those described in Covid-19. Objetive To evaluate how LUS findings correlate with chest computed tomography (CT) in patients admitted to the emergency department (ED) with suspicion of Covid-19. Methods Cross-sectional study of 20 patients (median age 43 years; interquartile range, 37-63 years; 50% male). All patients underwent LUS and chest CT on the day of ED admission. Each hemithorax was divided into 6 segments with similar landmarks, and equivalent scores (sc) of lesion severity were defined for both methods. The number of affected segments on LUS (LUSseg) was divided into tertiles (0-1, 2-5, and ≥6), and compared with number of affected segments on CT (CTseg), LUSsc, CTsc, and percentage of affected lung parenchyma through visual analysis (CTvis). ANOVA or Kruskal-Wallis test for continuous variables, chi-square test for categorical variables, and receiver operating characteristic (ROC) curve analysis to define optimal cutoff points were performed. P<0.05 was considered statistically significant. Results Median LUSsc, CTsc, CTseg, and CTvis were significantly different between groups. A clear separation between groups was demonstrated; patients with <2 affected segments on LUS were defined as low risk. The ROC curve showed good discriminative power to predict ≥6 affected segments on CT, with an area under the curve (AUC) of 0.97 and 0.98 for >7 LUSsc and >3 LUSseg, respectively. Conclusion LUS findings correlate with chest CT, and can help identify patients with normal lung or minor pulmonary involvement secondary to Covid-19. Int J Cardiovasc Sci. 2020; [online].ahead print, PP.0-0
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Tomography, X-Ray Computed/methods , Ultrasonography/methods , Cross-Sectional Studies , Triage/methods , Emergency Service, Hospital , COVID-19/diagnosisABSTRACT
Os autores descrevem o caso de uma paciente jovem com amenorreia primária e caracteres sexuais secundários normais. A investigação diagnóstica constatou a ocorrência da síndrome de Mayer-Rokitansky-Kuster-Hauser.
The authors describe the case of a young female patient with primary amenorrhea and normal secondary sexual characteristics. The diagnostic investigation demonstrated the occurrence of Mayer-Rokitansky-Kuster-Hauser's syndrome.
Subject(s)
Humans , Female , Adolescent , Congenital Abnormalities/diagnosis , Mullerian Ducts/abnormalities , Urogenital Abnormalities , Vagina , Amenorrhea , UltrasonographyABSTRACT
Tendo em vista a polêmica que ainda causa a realizaçäo do tratamento dos canais com necrose e lesäo apical em uma única sessäo, os coordenadores dos cursos de Endodontia das Faculdades Brasileiras receberam um questionário que objetivou verificar o percentual de tal procedimento em suas clínicas, possibilitando a realizaçäo de um panorama nacional da filosofia da obturaçäo imediata em dentes necróticos com lesäo. Pôde-se comprovar que a maioria dos cursos de graduaçäo de Endodontia näo realiza a obturaçäo imediata em dentes necróticos com lesäo periapical, mesmo após realizarem os passos essenciais que fundamentam cientificamente tal conduta
Subject(s)
Root Canal Obturation/statistics & numerical data , Root Canal Obturation/trends , Surveys and Questionnaires , Root Canal Therapy , Root Canal Therapy/trends , Schools, DentalABSTRACT
O presente estudo avalia a situaçäo do tratamento endodôntico em sessäo única de dentes necrosados com lesäo apical nas Universidades dos Estados Unidos da América. Foi enviada a cada Universidade uma carta explicativa com um questionário contendo 8 perguntas objetivas e 1 pergunta subjetiva. Totlizaram 61 cartas enviadas e 47 respondidas. A partir dos resultados concluímos que o tema ainda gera certa polêmica, porém a maior parte das Universidades pratica o tratamento de dentes sem vitalidade pulpar e com lesäo periapical em sessäo única
Subject(s)
Philosophy, Dental , Root Canal Obturation , Universities , United StatesABSTRACT
Durante a estação reprodutiva (março e abril), dois experimentos foram conduzidos com 116 ovelhas da raça Comedale, objetivando verificar o momento de ovulação nesta raça após estro natural ou induzido com ou sem o "efeito macho". As ovelhas foram submetidas a laparoscopia em intervalos de quatro horas entre 20 e 40 horas depois da identificação do início do cio natural e entre 48 e 120 horas em cada uma de duas repetições após a remoção dos pessários impregnados com 50mg de medroxiprogesterona e injeção de 500UI de eCG (gonadotrofina sérica equina)ou até a ovulação ser observada. Após o cio natural, 96 por cento de 56 ovelhas ovularam sendo a maioria (85 por cento) entre 24 e 32 horas do início do cio. No grupo de 60 ovelhas submetido a indução de cio foi constatado que na média as ovulações ocorreram as 65,1±2,2 horas e 73,8±3,2 horas após a remoção dos pessários, respectivamente, para os grupos submetidos ou não ao efeito macho (P < 0,05). As ovulações não foram afetadas pela idade das ovelhas e repetição dos tratamentos hormonais. O momento de ovulação após o cio natural apresenta pouca variação, já após cio induzido constatou-se antecipação nas ovulações com o efeito macho sem alteração na amplitude de variação, fato este, que pode ser responsável pela variabilidade nas taxas de concepção após inseminação com sêmen congelado.
The aim of the present study was to verify the time of ovulation after natural or induced estrus in the Comedale ewe. The ram effect was also evaluated in the presence of induced estrus. Both treatments were examined by laparoscopy every four hours, from 20h to 40h after beginning the natural estrus, and from 48h to 120h after withdrawing the sponges or until ovulation was observed. After natural estrus, 96 percent from 56 ewes had ovulated, and most of the ovulations (85 percent) had occurred from 24 to 32h after the onset of heat. The mean time of ovulation in 60 ewes treated with progestagen pessaries (50mg, MAP, 12 days) and eCG injection (500IU at sponge withdrawai) was 65.1 ± 2.2h and 73.8 ± 3.2h respectively for groups with and without the presence of rams. This trait was affected by the ram effect (P < 0.05); however, it was neither influenced by the age of the ewes nor the repeated hormonal treatments. The time of ovulation after natural estrus, due to its small variation, is not likely to affect the results of artificial insemination with frozen semen. On the contrary, the time of ovulation, but not the range of ovulation distribution, was significantly increased in ewes with induced estrus when in the presence of rams. These results probably play a role in the success rate of the artificial insemination with frozen semen.