ABSTRACT
Industrial exposure to toxic agent may produce a wide variety of respiratory damage. Acetic acid is a colorless liquid with a pungent vingar-like odor. It is a rare case that acute lung injury is caused by inhalation of acetic acid. Acetic acid is miscible with water, and may directly produce damage to mucosa of respiratory tract due to its irritant quality. The outcome of the reaction is dependent on the intensity and duration of exposure and varies from death or pulmonary edema in acute phase to resolution or bronchiolitis obliterans or bronchiectasis. We experienced a rose of acute lung injury due to accidental inhalation of acetic acid. The patient was a 31-year-old male who had developed progressive chest discomfort, chilling sense, and mild dyspnea after accidental inhalation of acetic acid. He had severe hypoxemia and chest radiograph showed diane bilateral alveolar edema. He responded to conservative treatment with oxygen inhalation and was discharged with improved condition on the 7th hospital day.
Subject(s)
Adult , Humans , Male , Acetic Acid , Acute Lung Injury , Hypoxia , Bronchiectasis , Bronchiolitis Obliterans , Dyspnea , Edema , Inhalation , Mucous Membrane , Odorants , Oxygen , Pulmonary Edema , Radiography, Thoracic , Respiratory System , Thorax , WaterABSTRACT
Authors experienced a case of Morquio' s syndrome accompanied by respiratory failure in a aged fifteen year old boy. Patient showed normal intelligence, but stunted growth with short trunk and unproportionately large head, pectus carinatum, kyposcoliosis, muscular weakness, paralysis and genu valgum. No other member of family was affected with this syndrome. There were radiological findings of subluxation between first and second cervical vertevrae, central beaking with thoracolumbar vertebra plana, wine glass appeared pelvis and shortening of carpal & metacarpal bones of both hands. There were biochemical findings of large proportion of chondroitin sulfate (87%) on urinary mucopolysaccharides examination. Resipratory failure occurred due to compression of cervical spinal cord by subluxation between first and second cervival vertebra. He was maintanied by ventilator, discharged. And he died.
Subject(s)
Animals , Humans , Male , Beak , Chondroitin Sulfates , Genu Valgum , Glass , Glycosaminoglycans , Hand , Head , Intelligence , Metacarpal Bones , Muscle Weakness , Paralysis , Pelvis , Respiratory Insufficiency , Spinal Cord , Spine , Ventilators, Mechanical , WineABSTRACT
No abstract available.
ABSTRACT
No abstract available.
ABSTRACT
The author studied 294 cased of childhood thyroid disorder at Pediatrics Department in Pusan National University Hospital from Jan. 1984 to Dec. 1991. The patients with grouped according to thyroid function and disease entity, and were evaluated symptoms and signs, laboratory findings and treatment. The results were summarized as follow 1) The childhood thyroid disorder was the most common in the older children, but congenital hypothyroidism was the most frequent in the early infancy. The ratio of male and female was 1:4.6, but in congenital hypothyroidism, it was 1:1.7. 2) In classification of thyroid disorder according to thyroid function, euthyroidism was the most common with 73% of the patients, hypothyroidism was 15% and hyperthyroidism was 12% in order. in hypothyroidism. the majority was Graves' disease and a few cases were Hashimoto's thyroiditis. In Euthyroidism, simple goiter was the most common with 72%, Hashimoto's thyroiditis was 24%,and 3 cases were thyroid cancer. In hypothyroidism. congenital hypothyroidism was 44% and Hashimoto's thyroiditis was the most common cause of congenital hypothyroidism. 3) The clinical manifestation at first visit hypothyroidism included thyroid enlargement which was seen in all cases, cold sweating,palpitation and nervousness. In Euthyroidism, there was no specific complaints except thyroid enlargement. Growth retardation, constipation and mental retardation were visible in congenital hypothyroidism. In acquired hypothyroidism, the patents complained thyroid enlargement, lethargy, anorexia. The causes of congenital hypothyroidism was ectopic thyroid, aplasia or hypoplasia of thyroid and dyshormonogensis with similar frequency. 4) In most cases of hyperthyroidism, propylthiouracil was administerd. The half of the patients were recovered at 4 weeks after treatment, and 92% of them were recoverd at 3 months later after treatment. The side effects were rare. In a few of them surgical method was underwent. In hypothyroidism. L-thyroxine was adminisetered, and the result was excellent.
Subject(s)
Child , Female , Humans , Male , Anorexia , Anxiety , Classification , Congenital Hypothyroidism , Constipation , Goiter , Graves Disease , Hyperthyroidism , Hypothyroidism , Intellectual Disability , Lethargy , Pediatrics , Propylthiouracil , Thyroid Dysgenesis , Thyroid Gland , Thyroid Neoplasms , Thyroiditis , ThyroxineABSTRACT
The author analysed foreign body in the airway, divided into two groups vegetable foreign body group(VFBG) and non-vegetable foreign body group(N-VFBG), according to the nature, in 88 patients aged from 5 months to 15 years who were diagnosed and treated under ventilating bronchos-copy at Department of Pediatrics and Otolaryngology, Pusan National University Hospital from 1980 to 1990. Of the 88 patients analysed, 13 were followed for review, which comprised clinical assessment, chest radiography, and perfusion lung scan. The follwing results were obtained. 1) The highest incidence was seen in the age group of 1 to 3 years old especially in VFBG, bur no difference in incidence among each age group was observed in N-VFBG, The ratio of incidence between male to female was 2:1 ein total and, in N-VFBG, the incidence of male 8 times higher than female. 2) A wide variety of foreign bodies was recovered, with peanut being by far the most common (50%) and the ratio of incidence between VFBG and N-VFBG was 6 to 4. 3) The time interval of less than 24 hours between aspiration and admission was most frequently seen in 38% and of more than 3 weeks in 11%. The time interval in VFBG and the group with left bronchial lodging was longer than of N-VFBG and the group with right bronchial lodging, each respectively but no statistical difference was observed. The time interval in the group with bronchial lodging was significantly longer than of the group with laryngeal and tracheal lodging. 4) Frequent symptoms and signs were coughing, dyspnea, fever, decreased air entry, coarse breathing sound and rales. In total, clinical manifestations were more common in VFBG, especially in the incidence of fever, decreased air entry, coarse breathing sound and rhonchi. 5) The roentgenographic findings on admission were emphysema, pneumonia and atelectasis in the order of frequency. The incidence of emphysema and complex roentgenographic findings were more common in VFBG whereas in N-VFBG radioopaque foreign body normal roentgenographic findings were more common. 6) The prevalence of bronchial lodging was over 70% regardless of age group. No difference of predilection was observed between right and left bronchial lodging before 7 years old, but after 7 years old right bronchial lodging was significantly seen. 7) The longer the time lag before admission after aspiration, the longer the duration of hospitalization was in VFBG but with no statistical significance. However, no correlation between time lag and the duration o hospitalization was observed in N-VFBG. The group with bronchial lodging had significantly longer duration of hospitalization compare to that of the group with laryngeal and tracheal lodging, The group with left bronchial lodging had longer duration of hospitalization compare to that of the group with right bronchial lodging but with no statical significance. 8) Of the 13 cases reviewed, one had abnormal lung perfusion scan in spite of normal clinical assessment and chest X-ray, who was treated on 20 days days after aspiration of peanut in the right bronchus.
Subject(s)
Child , Child, Preschool , Female , Humans , Male , Bronchi , Cough , Dyspnea , Emphysema , Fever , Follow-Up Studies , Foreign Bodies , Hospitalization , Incidence , Lung , Otolaryngology , Pediatrics , Perfusion , Pneumonia , Prevalence , Pulmonary Atelectasis , Radiography , Respiratory Sounds , Thorax , VegetablesABSTRACT
To evaluate the atlantoaxial instability in children with Down syndrome, the authors analyzed the 97 children with Down syndrome attending to 2 schools for handicaped children in Pusan. The rsults of study were as follows; 1)The incidence of atlantoaxial instability in 97 individuals with Down syndrome was 8(8.3%) in neutral position and in 10(10.3%) in flexion, respectively. 2) The mean atlantoaxial gap was significantly higher in patients with Down syndrome than in the control group(P<0.05). 3) The mean atlantoaxial gaps in patients with Down stydrome according neck position was significantly higher in flexion(3.27 +/-1.08mm)than in neutral(2.63 +/-1.18)(p<0.05). 4) When mean atlantoaxial gaps of patients with Down syndrome were analyzed according to age groups, young age groups were statistically higher than old age groups in flexion position(p<0.05) but no statistically signigican differences were in neutral position. 5) The mean atlantoaxial gap of obese group was slightly higher than those of non-obese group but no statistically significant difference was noted(p<0.05).
Subject(s)
Child , Humans , Down Syndrome , Incidence , NeckABSTRACT
The auther analysed 29 patients who were treated with prednisolone, including nephrotic syndrome (13 cases), acute leukemia(10 cases), bronchial asthma (2 cases), juvenile rheumatoid arthritis (2 cases) and ulcerative colitis (1 cases) patients in childhood, after remission induction, pro9longed alternate or interrupted treatment was used. The auther observed patterns of height velocity of these patients from 1.6 to 10.3 years. The results were as follow 1) Of the total 29 patients who were treated with prednisolone, most of them showed normal height velocity within the percentile channels, but 4 cases (13.8%) of them showed delay in height velocity. 2) The 4 cases who delayed in height velocity, including 2 cases of bronchial asthma and 2 cases of juvenile rheumatoid arthritis patients, received prednisolone daily about 0.4~1.5mg/kg from 3 to 6 years alternatively or interruptedly. Height velocity was decreased from bet ween 3 and 25 percentile channel at first to below 3 percentile channel at last contiously. 3) In these 4 cases, height velocity was inversely proportion to dosage of prednisolone.
Subject(s)
Humans , Arthritis, Juvenile , Asthma , Colitis, Ulcerative , Nephrotic Syndrome , Prednisolone , Remission InductionABSTRACT
Xanthogranulomatous pyelonephritis, an uncommon chronic inflammatory renal disorder of middle-aged women, is rarely seen in childhood. A 10 year-old boy with focal type of this disease in upper and lower pole was experienced. Patient had a intermittent fever and right flank pain without palpable mass. The blood analysis only revealed ESR increase but no anemia, no leukocytosis. There was no history or signs of urinary tract infection or calculi. The urine analysis and culture showed nothing abnormal. An intravenous pyelogram, ultrasonogram, abdominal CT and selective renal arteriography only demonstrated a non functioning upper pole of right kidney. During operation, a gross finding and frozen section strongly showed xanthogranulomatous pyelonephritis and diagnosis was made on histological examination, After nephrectomy, there had been no evidence of disease recurrence during 2 years follow-up period.
Subject(s)
Child , Female , Humans , Male , Anemia , Angiography , Calculi , Diagnosis , Fever , Flank Pain , Follow-Up Studies , Frozen Sections , Kidney , Leukocytosis , Nephrectomy , Pyelonephritis, Xanthogranulomatous , Recurrence , Tomography, X-Ray Computed , Ultrasonography , Urinary Tract InfectionsABSTRACT
No abstract available.
Subject(s)
Protein C Deficiency , Protein C , Purpura Fulminans , PurpuraABSTRACT
No abstract available.
Subject(s)
Female , Humans , Infant, Newborn , Pregnancy , Pregnancy in AdolescenceABSTRACT
No abstract available.