Synchronous tumours of large intestine

The synchronous presentation of multiple adenocarcinomas is an unusual but well recognized event accounting for approximately 3-12 percent of these tumours. All patients with colorectal cancers should be fully evaluated before surgery. Preoperatively, pancolonoscopy and barium studies help in identifying these neoplasms. Careful examination of the whole large gut during operation for colonic malignancy and intraoperative colonoscopy eliminate the chances of these tumours. We present a case of synchronous large gut adenocarcinomas

Experience with somatostatin analogue [octreotide] in gastrointestinal and pancreatic fistulae

Over a period of 2 years Somatostatin analogue [Octreotide] was administrated to 12 patients with enterocutaneous [EC] and 2 patients with pancreatic fistulae [PF] in a daily dose of 300ug/24 hr. There were 8 male and 6 female patients with an average age of 30.3 years [range 10-65 years]. In 9 patients with EC low output fistulae there was spontaneous closure and at least 50% reduction in 2 patients with high output fistulae which required further surgery. The two cases of pancreatic fistula also closed spontaneously in 5 to 8 days. Mean period for closure in 9 cases was 7.4 days [range 5-12 days]. There were fewer side effects and one death in high output fistula due to over whelming infection and septicemia. The results of this study favour the use of Octreotide in EC and pancreatic fistulae