ABSTRACT
Objective To evaluate efficiency of brain metastases tumor using X-knife under farctionational stereotactie radiotherapy (FSRT) combine with whole brain radiotherapy (WBRT). Methods Retrospective comparing 51 patients treated by FSRT plus WBRT (FSRT + WBRT group) with 35 patients treated by WBRT alone (WBRT group) on the effecting rate and survival rate. Results The completeness response rate was 49 % and 26 % (P < 0.05) in FSRT + WBRT and WBRT groups, respectively. The effecting rate was 80 % and 71 % (P 0.05) in FSRT + WBRT and WBRT groups, respectively. The middle survival time was (11.0 ± 1.5) months and (6.5 ± 0.5) months (P < 0.05) in FSRT + WBRT and WBRT groups, respeetivley. The 0.5-, 1.0- and 1.5-years survival rate was 63 % and 41 % (P 0.05), 51 % and 23 % (P 0.05) and 24 % and 9 % (P < 0.05) in FSRT + WBRT and WBRT groups, respectively. Conclusions The method with FSRT plus WBRT in the treatment of brain metastases tumor is safe and relieved focal symptom of patients quickly with lesser injury on normal tissue and the survival time be prolonged, it has better therapeutic effects than WBRT alone for treating brain metastases tumor.
ABSTRACT
Objective To observe CT findings of brain malignant tumor treated by X-knife. Methods 59 patients of brain malignant tumors after the treatment of X-knife were underwent plain and enhanced CT scan.According to the rate of disappearance,the density,the changes of edema and the radioactive encephalitis,all patients were followed up. Results Metastatic brain tumor disappeared faster than primary ones,the more extensively primitive tumors in metastasis disappeared more rapidly.Lymphoma and germinoma disappeared faster than astrocytoma.The low density tumors did not recured,the middle density tumors without enhancemant recured difficultly and the blend density tumors with middle enhancenent recured easily.Conclusion Plain and enhanced CT scan can be a good standard to demostrate the effect and prognosis of brain malignant tumor after X-knife treatment.