ABSTRACT
@#Teriparatide has been known to aid in the treatment of osteoporosis but its use in the management of fracture disorders is poorly documented. This review aims to show that teriparatide administration may improve the healing process in fractures that fail to unite after sustaining trauma. A total of 22 reported cases have been identifi ed from 2009 to 2017. Teriparatide doses were given in a median duration of 5.6 months with a median time to complete union of 8.5 months. This review systematically summarizes all clinical case reports of non-union treated with teriparatide for us to gain insight into its off-label use.
Subject(s)
TeriparatideABSTRACT
Background@#Tuberculosis arthritis is a type of extrapulmonary manifestation of tuberculosis (TB) and can be seen in many clinical forms, especially in developing countries.@*Aims@#This study will look into the quality of life (QoL) of patients who were diagnosed with tuberculous arthropathy of the extremity and underwent surgery at the University of Santo Tomas Hospital (USTH) from January 2014 to December 2016 using the Tagalog SF – 36 questionnaire.@*Methods@#All patients who underwent surgery for TB arthropathy at USTH for three years were included. The Tagalog SF – 36 questionnaire was administered to the patients during follow-up to assess the QoL scores. A detailed evaluation of the questions was performed to depict any pattern on specii c areas that affect the QoL of patients.@*Results@#Patients who underwent surgery scored high for role emotional (mean 93.33) and lowest on the bodily pain scale (mean 69.2). Higher physical component scores (PCS) were noted in patients who underwent surgery in 2014 compared to 2015 and 2016. Higher mental component scores (MCS) scores were also noted in patients operated in 2014 compared to 2015 and 2016. All patients have good QoL scores after surgery and complete medical treatment as demonstrated by the SF-36 scores. Tuberculous arthropathy can affect the physical and mental aspects of patients. No signii cant difference in mean scores by year were seen in all the scales of the SF-36 (p = >0.05).@*Conclusion@#All patients have good QoL scores after surgery and complete medical treatment as demonstrated by the SF-36 scores. QoL scores showed more improvement as the duration post-treatment is longer.