ABSTRACT
ABSTRACT Introduction: Extracorporeal membrane oxygenation (ECMO) is the first-line therapy for temporary mechanical circulatory support allowing cardiac and pulmonary recovery or as a bridge to further therapeutic alternatives. The aim of this study was to report clinical outcomes in adult patients with refractory cardiac failure after open-heart surgery undergoing ECMO in a single center with an ECMO unit in Chile. Methods: We retrospectively analyzed adults with refractory cardiac failure after open-heart surgery who required a venoarterial (VA) ECMO between 2016 and 2021. Results: Of 16 patients with VA ECMO, 60% were men (n=10), 90% had hypertension (n=14), 69% had < 30% of left ventricular ejection fraction (n=11), and the mean European System for Cardiac Operative Risk Evaluation II score was 12 ± 11%. ECMO support with central cannulation accounts for 81% (n=13), and an intra-aortic balloon pump was used in nine patients (56%). The mean time of support was 4.7 ± 2.6 days (1.5 - 12 days). ECMO weaning was achieved in 88% of patients, and in-hospital mortality was 44% (n=7) after discharge. The freedom from all-cause mortality at one year of follow-up of the entire cohort was 38% (n=6). Conclusion: VA ECMO is now a well-known life-saving therapeutic option, but mortality and morbidity remain high. Implementation of an ECMO program with educational training is mandatory in order to find the proper balance between patient benefits, ethical considerations, and public health financial input in South America.
ABSTRACT
El siguiente trabajo detalla un enfoque integral para la evaluación y el manejo intraoperatorio de la cirugía en la válvula mitral. Los avances tecnológicos han hecho de esta técnica un instrumento fundamental en el manejo intraoperatorio de estos pacientes. Las nuevas técnicas quirúrgicas de reparación de la válvula mitocondrial han determinado que el abordaje ecotransesofágico bi-dimensional se ha convertido en un examen de rutina, sin embargo, el advenimiento del ultrasonido tridimensional (3D) nos ha permitido aprender más sobre la anatomía funcional de la regurgitación de la válvula mitral, el mecanismo fisiopatológico predominante, y realizar evaluaciones en tiempo real de los resultados de una reparación o reemplazo quirúrgico. Estas contribuciones han contribuido a la capacidad de toma de decisiones de los equipos quirúrgicos, resultando en una mayor tasa de éxito para la reparación de la válvula mitral y una reducción de las complicaciones quirúrgicas.
The following work details an integral approach to the evaluation and intraoperative management of surgery on the mitral valve. Advances in technology have made this technique a fundamental instrument in the intraoperative management of these patients. The new surgical techniques of mitochondrial valve repair have determined that the bi-dimensional ecotransesophageal approach has become a routine examination, however, the advent of three-dimensional ultrasound (3D) has allowed us to learn more about the functional anatomy of the mitral valve's regurgitation, the predominant pathophysiological mechanism, and to conduct real-time evaluations of the results of a surgical repair or replacement. These contributions have contributed to surgical teams' decision-making capabilities, resulting in a greater success rate for mitral valve repair and a reduction of surgical complications.
O seguinte trabalho, faz uma abordagem integral da avaliação e manipulação intraoperatória da cirurgia na valva mitral. Os avanços na tecnologia tem feito dessa técnica um instrumento fundamental na manipulação intraoperatória desses pacientes. As novas técnicas cirúrgicas de reparação valvar mitral determinaram que a ecocardiografía transesofágica bidimensional tornou se um exame de rotina, no entanto o ultrassom tridimensional (3d) nos permitiu saber mais sobre a anatomia funcional da valva mitral, o mecanismo fisiopatológico predominante, assim como a avaliação em tempo real dos resultados da reparação ou substituição cirúrgica. Essas contribuições tem contribuído para a toma de decisões da equipe cirúrgica resultando numa maior taxa de sucesso de plastias da válvula mitral, assim como uma redução nas complicações cirúrgicas.