ABSTRACT
Background: Genetics plays an important role in the detection of an Oral potentially malignant lesion. A major contributor to genetic study is Dermatoglyphics or the study of fingerprints and lines of palmer and plantar surfaces. Many researchers have used dermatoglyphics to connect genetics with oral lesions and malignancies. Thus, the current study has been conducted to find out an association between dermatoglyphic patterns and oral leukoplakia, oral submucous fibrosis and healthy subjects.Methods: The present study is conducted on subjects that have been already diagnosed with oral lesions. Fingerprint patterns (whorled, loop and arch) were evaluated by utilizing fingerprints.Results: The present study showed that the loop pattern was common in all three subjects. The frequency of whorled and arch pattern is decreased in oral leukoplakia and oral submucous fibrosis that healthy subjects. Arch pattern is comparatively decreased in subjects with oral leukoplakia than oral submucous fibrosis and there is a decrease in the frequency of whorled patterns in OSMF as compared to oral leukoplakia.Conclusions: Authors conclude that simply by observing the whorled and arch patterns in a subject, authors can hypothesize that risk of occurrence of oral leukoplakia and oral submucous Fibrosis and take preventive measures against the said lesions.
ABSTRACT
Background: Cognitive deficits among patients with schizophrenia are now recognized as being widelyprevalent and one of the most disabling aspects of the illness, as they are associated with poor functionaloutcomes. Psychotropic medications and benzodiazepines, which are often used in these patients couldimpact cognition as could the extrapyramidal side-effects. Yet, here are hardly any Indian studies on thesubject. The aim of this study was to determine whether cognitive dysfunction among patients withschizophrenia is associated with extrapyramidal symptoms, anticholinergic burden of psychotropic drugsand benzodiazepine dosageMethodology: 40 clinically stable, out-patients suffering from schizophrenia, without any pre-existingneurological disorders between the ages of 18 to 60 years, who had been compliant with medications wereselected. Extrapyramidal symptoms (EPS) were assessed using the modified Simpson-Angus scale,anticholinergic burden (ACB) was evaluated using the Anticholinergic burden scale. The benzodiazepinedosage was noted. Cognition was assessed using the Stroop Color and Word Test and the Wisconsin Cardsorting test. The correlations between scores on EPS and ACB and neuropsychological tests were carriedout using partial correlations controlling for positive and negative symptoms.Results: There were no significant associations noted between extrapyramidal symptoms, anticholinergicburden, benzodiazepine dosage and performance on the neurocognitive tests used.Conclusion: Methodological differences make it difficult to construct comparisons across studies but thereis some evidence to support our findings
ABSTRACT
Introduction: Coping skills adopted by patients suffering from chronic diseases such as Polycystic OvarianSyndrome (PCOS) can impact the psychological well-being and outcome. This however has not beenadequately studied in India. The aims of the study were to to study the type of coping skills used by thepatients of PCOS, to evaluate any difference in coping skills between patients with and without psychiatricco-morbidity and to study any correlation between coping skills and quality of life and body-mass index.Materials and Methods: 70 females in the reproductive age group (18-45 years) diagnosed with PCOS asper Rotterdam’s Criteria without any pre-existing psychiatric illness were clinically interviewed forpresence of anxiety and depression. Their coping skills were assessed using Brief Cope Scale. Their qualityof life was evaluated using World Health Organization Quality Of Life –BREF Scale. The scores werecompared using paired and unpaired t test and ANOVA.Results: Patients used both adaptive and maladaptive coping skills but scores on adaptive coping skillswere higher than those on maladaptive coping. Problem focused coping was significantly higher than bothemotional coping and dysfunctional coping. There was no significant difference in the coping skills inpatients with and without psychiatric morbidity. There was no significant correlation between coping andquality of life and body-mass index.Conclusion: Coping skills did not have a significant impact on the psychiatric morbidity or quality of lifeor body-mass index among patient with PCOS.