Management of Twak vikruti: a case report

In today抯 era skin disease is very commonly found. As there is no specific and permanent treatment available in modern science therefore people are attracting towards Ayurvedic treatments for skin related issues and diseases. Twak(skin) is the largest organ of human body which protects and covers whole body. It is one of five gyanendriya that is Sparsh gyanendriya(sense organ). Nowadays people use so many chemical products internally as well as externally for looking good which causes the imbalance of dosh, dhatuand mala (fecal product). These are the fundaments of human body and skin is the outer most protective organ. So, whenever anything uncommon happened with body, skin start showing some symptoms like redness, swelling, due to dushti of doshas (imbalance/toxicity of dosha).A male patient of 36years old came in our hospital with the complains of Twak kandu(skin itching), Krushna varnata (hyper pigmentation), Krushna varni pitikotpatti (rashes), Vali(wrinkles) and Rukshta(dryness) which was diagnosed as Twak vikruti(skin disease) and treated with complete ayurvedic treatment Shaman chikitsa(internal medicine) along with Shodhan chikitsa(body purification treatment).

Association of Early-Onset Sepsis and Vitamin D Deficiency in Term Neonates

Objective: To determine if vitamin D status is affected in term neonates with early onsetsepsis and its association with outcome. Methods: Study was done at a level 3 neonatal uniton 140 neonates. Term neonates with early onset sepsis (study group, 70 patients) andwithout sepsis (control group, 70 patients) were enrolled. Results: Mean neonatal vitaminD level in the study group was 16.00 (10.49) ng/mL and in the control group, was29.07(8.36) ng/mL (P =0.061). In the study group 80% (n=56) babies had low vitamin Dlevels (<32 ng/mL) among whom 51.7% (n=29) had severe vitamin D deficiency (<11ng/mL).In the control group, 58.5% (n=41) had low vitamin D levels of whom, 9.8% (n=4) hadsevere vitamin D deficiency (P<0.001 and P<0.001, respectively). Mortality and highlyprobable sepsis were more common with vitamin D levels <11ng/mL in the study group(P= 0.005 and P=0.006, respectively). Conclusion: Vitamin D is deficient in neonates withearly onset sepsis and is associated with increased sepsis severity and mortality.