ABSTRACT
Background: Yoga includes combination of postural exercise (Asanas),Voluntary breathing exercise (pranayam) & relaxation techniques. The comparative study about effects of regular practice of yoga & physical exercise on cardio-respiratory functions and respiratory pressures (MIP,MEP) is very important to better understand it’s effect on health. Method: 200 healthy volunteers (146M-54F) from age group (17 -26)years were included in the study.They were divided in to two groups. Gr A Yoga group(n=100),Gr B Physical exercise group(n=100). Yoga group practiced some yoga exercises including Asanas,Pranayam & relaxation postures daily one hour for 3 months.While Physical exercise group practiced slow walk,calisthenic exercise & stretching exercises daily 1 hour for 3 months. Following parameters were recorded at start & end of the study. Resting cardiovascular parameters including HR,BP,PP,MAP,RPP & DoP were recorded. Pulmonary parameters (FVC,FEV1,FEV1/FVC,PEFR,MVV) were recorded. Apart from this MIP,MEP & 40mmhg endurance test were also recorded .Result: Yoga group shows significant reduction in Heart rate (p<.01),SBP & DBP (p<.05), MAP(p<.01),while exercise group shows only decreasing trend. FVC & FEV1 inreased significantly after yoga training. FEV1/FVC, PEFR & FEF25-75% shows increasing trend in both the groups,but only exercise group shows significantly raised PEFR & FEF25-75%. MVV was significantly improved in yoga group. MIP,MEP were significantly increased after yoga training. Timing of Respiratory Endurance test was also significantly raised(p<.05) in yoga group. Conclusion: 3 moths Yoga training produces a significant improvement in respiratory pressures (MIP,MEP), spirometric values.
ABSTRACT
Background: Garlic is naturally occurring sulphur containing dietary agent belong to Allium family. Members of this family i.e. Garlic, Onions are found to have beneficial effect on atherosclerosis and ischemic heart diseases in both experimental animals and in human beings. Objective: To compare the potency of garlic as antihyperlipidemic and antiplatelet and antithrombotic between its watery and alcoholic extract for their effects. Methods: 25 guinea pigs were fed cholesterol (0.5g/kg body weight) for an initial period of 4 weeks. Cholesterol was then discontinued and the animals were divided into 3 groups. Group-I (n=7) was fed with stock diet and was taken as control. Group-II (n=9) was given 1ml of watery extract and Group-III (n=9) was fed with 1ml of alcoholic extract of garlic with normal diet daily for 4 weeks. The garlic content of both the extract was 2 gm/ml by wt/vol. Fasting blood samples were collected at the end 4 weeks and finally at the end of the study i.e.8 weeks for estimation of serum cholesterol, serum triglyceride, LDC-C, HDL-C, VLDL-C,atherogenic index and platelet adhesiveness index. Bleeding time and clotting time were also detected in all the 3 groups.Results: In the present study, the watery and alcoholic extract of garlic shows significant hypolipidemic activity as they reduced significantly serum cholesterol, serum triglyceride, LDC-C, VLDL-C and atheriogenic index in hyperlipidemic guinea pigs (p<0.01) compared to control. The significant rise in HDL-C was observed in group II but not in group III animals. On comparison between two extracts, watery extract of garlic was more potent hypolipidemic agent, compared to alcoholic extract. Both extract significantly reduces platelet adhesiveness and bleeding time. But between two extract the watery extract was found more potent anti-thrombotic agent as it showed significant decrease in platelet adhesiveness (P<0.01). BT was significantly increased in group II compared to group I and III. Conclusion: It can be concluded that watery extract of Allium Sativum is more potent hypolipidemic and antiplatelet, and anti-thrombotic agent.
ABSTRACT
Gastric tissue histamine concentration was determined 14 days after mock subdiaphragmatic vagotomy, subdiaphragmatic vagotomy, mock bilateral adrenalectomy and bilateral adrenalectomy in four different groups of animals and the results were compared with those of control rats. The results show that neither of the experimental situations of mock subdiaphragmatic vagotomy, subdiaphragmatic vagotomy and mock bilateral adrenalectomy could bring about any significant change in gastric tissue histamine concentration fourteen days after the respective operations, whereas, following bilateral adrenalectomy, the gastric tissue histamine concentration went up to two and half times the basal level during the same period thus indicating that by removal of adrenal influences there was an increase in synthesis and storage of histamine in the stomach wall.