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Journal of Biomedical Engineering ; (6): 680-683, 2015.
Article in Chinese | WPRIM | ID: wpr-359586

ABSTRACT

The regulation of epigenetics on bone marrow mesenchymal stem cells (BMSCs) has been a research hot spot in medical area. This paper mainly summarizes the progress of the regulation of DNA methylation, histone acetylation, small interfering RNA (siRNA) induced gene silence and microRNA (miRNA) on BMSCs. Our analysis shows that the regulation of epigenetics on BMSCs plays a significant role in the repair of bone tissue, nervous tissue and cardiac muscle.


Subject(s)
Humans , Acetylation , Bone and Bones , DNA Methylation , Epigenesis, Genetic , Hematopoietic Stem Cells , Histones , Mesenchymal Stem Cells , Cell Biology , MicroRNAs , Myocardium , RNA, Small Interfering , Wound Healing
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