1.
Journal of Leukemia & Lymphoma
;
(12): 1-3,11, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-603330
ABSTRACT
How to improve the efficacy of chimeric antigen receptor T-cell (CAR-T) is one of the key points for manufacture and application of CAR-T. In this review, the studies from the 57th American Society of Hematology (ASH) annual meeting regarding to the strategies for optimal CAR-T activity were summarized, including pathway inhibitors, enhancement antigen expression of target cells, optimization of conditioning chemotherapy, as well as the novel technology for CAR-T generation.