ABSTRACT
OBJECTIVES: To evaluate pregnancy outcomes after placental needle penetration during midtrimester diagnostic amniocentesis. METHODS: We collected 726 singleton pregnancy cases from 1054 pregnancies of midtrime-ster diagnostic amniocentesis, and analysed pregnancy outcomes after the procedure based on medical records. To compare the outcomes, we divided 726 cases into two groups; placental penetration group by aspiration needle(170 cases) and non-penetration group(556 cases). RESULTS: There were no statistically significant differences between two groups about maternal age and gestational age at the time of procedure, and the distribution of amniocentesis indication. In comparison of complications between two groups after procedure, a. There was no statistically significant difference in amniotic fluid leakage: in penetration group, 1 case (0.58%) and in non-penetration group, 5 cases(0.89%) were observed. b. There was no statistically significant difference in vaginal bleeding: in penetration group, 2 cases (1.18%) and in non-penetration group, 3 cases(0.54%) were observed. c. There was no statistically significant difference in developing abruptio placentae: in penetration group, no case developed and in non-penetration group, one case(0.18%) was observed. d. As for fetal loss, there was no statistically significant difference : in penetration group, 4 cases (2.35%) and in non-penetration group, 10 cases(1.80%) were occurred. e. As for birth weight, there was no statistically significant difference : in penetration group, 3.26+/-0.8 kg and in non-penetration group, 3.21+/-0.9 kg were measured. CONCLUSION: Our study shows that placental penetration by aspiration needle during diagnostic mid-trimester amniocentesis does not increase the risk of post-procedure complication.
Subject(s)
Female , Humans , Pregnancy , Abruptio Placentae , Amniocentesis , Amniotic Fluid , Birth Weight , Gestational Age , Maternal Age , Medical Records , Needles , Pregnancy Outcome , Pregnancy Trimester, Second , Uterine HemorrhageABSTRACT
OBJECTIVE: The purpose of this study was to determine whether unexplained elevation of second-trimester maternal serum beta-human chorionic gonadotropin (beta-hCG) is associated with adverse pregnancy outcomes. METHOD: Between January 1998 and December 1999, we evaluated 2112 pregnant women undergoing second trimester triple marker screening test who delivered at our hospital. Inclusion criteria were singleton pregnancy, confirmed gestational age, and hCG level greater than 2.0 MoM. The exclusion criteria were fetal anomaly, abnormal karyotype, MSAFP level greater than 2.0 MoM, uE3 level less than 0.4 MoM, and referred patients with pregnancy-induced hypertension (PIH). A group of randomly selected women with normal maternal serum hCG and AFP levels served as control. RESULTS: Women with unexplained elevation of hCG level showed increased risks for PIH (p<0.001) and preterm delivery (p<0.003). There were no significant diffrences between study and control groups with respect to placental abruption, fetal distress, PROM, intrauterine fetal death, and apgar score. CONCLUSION: Pregnancies with unexplained elevation of hCG levels should be regarded as high-risk pregnancies and managed accordingly. The combination with these biomarkers such as VEGF, plasminogen activating factor I and AT-III as a screening test for PIH may be useful.
Subject(s)
Female , Humans , Pregnancy , Pregnancy , Abnormal Karyotype , Abruptio Placentae , Apgar Score , Biomarkers , Chorionic Gonadotropin , Fetal Death , Fetal Distress , Fibrinogen , Gestational Age , Hypertension, Pregnancy-Induced , Mass Screening , Plasminogen , Pregnancy Outcome , Pregnancy Trimester, Second , Pregnancy, High-Risk , Pregnant Women , Vascular Endothelial Growth Factor AABSTRACT
Prenatal Ultrasonographic findings of meconium peritonitis show calcificalion, and abdominal echogenic masses such as pseudocyst. Also, we can find availability of 3 dimensional ultrasonography above these descriptions. We present a case of meconium peritonitis in uterus which was diagnosed by means of prenatal 2D & 3D ultrasonography with brief review of literatures.