ABSTRACT
Elastography is an imaging technique to measure the stiffness of tissues. Images are acquired before and after soft compression of tissues and the deformation is evaluated. Strain ratio -calculated as the ratio of stiffness between nodular tissue and surrounding normal thyroid tissue. With prior verbal and written consent patients were examined on gray-scale ultrasound on transverse images and then using elastographic ultrasonography technique. patients were followed up by fnac findings & postoperative histopathology report in cases of inconclusive FNAC reports. This is prospective study conducted on 200 subjects at Government Medical College, Department of RADIO-DIAGNOSIS, Nagpur from November 2016 to 2018. Regarding sonoelastograph, relation between elastograph scores and thyroid malignancies showing sensitivity, specificity and p value is calculated. The most accurate strain ratio cutoff value among studies calculated. RESULTS: Ultrasound Strain elastography is a promising imaging technique that is useful in the differentiating between benign and malignant thyroid nodules. Further improvements in the technique and the diagnostic criteria are necessary for this examination to provide a useful contribution to diagnosis. The use of Real Time ultrasound strain elastography would lead to low thyroid FNAC’s because of the high elasticity of being strongly associated with a benign cytology.
ABSTRACT
Background: The purpose of present study was to identify sonologically, the cystic and non-cystic renal mass lesions, to attempt differentiating benign lesions from the malignant ones and to correlate ultrasound findings with ultra sonographically guided cytological or pathological findings.Methods: In this hospital based prospective observational study, all the patients with confirmed renal mass were subjected to USG guided fine needle aspiration cytology (FNAC). All the patients presenting with lump in abdomen, haematuria or pain in abdomen, wherein the clinical diagnosis of renal mass was being considered by the clinician, were enrolled for the study. Total 54 participants were enrolled. Those with confirmed renal mass were subjected to USG guided FNAC and which was carried out in supine position by transabdominal route in all patients.Results: About 42 participants were retained for final analysis; since FNAC was not possible in 12 patients. Pain in abdomen (36, 85.7%), mass in abdomen (34, 81%) were the most predominant clinical findings. Mixed echogenicity was the commonest echo pattern (42, 77.7%) on ultrasonography. Histopathologic/cytologic examination of the 39 malignant cases confirmed renal cell carcinoma (18, 46.5%) to be the commonest malignancy, followed by Wilms’ tumour (10, 26%). Out of the 39 cases in which clinico-radiological diagnoses were correlated with histo-cytological diagnoses, it was found to be consistent in 30 (77%) cases and inconsistent in 9 (23.1%) cases.Conclusions: Fine needle aspiration cytology/biopsy performed under ultrasonography guidance demonstrates high diagnostic accuracy. It is hence recommended as part of fundamental approach to the diagnosis of non-cystic renal mass.
ABSTRACT
Background: Early and accurate pathological diagnosis of skin cancers is vital. FNAC supposedly gives satisfactory results in diagnosis of nodular skin & subcutaneous lesions. Objective: To analyse the incidence of cutaneous/subcutaneous lesions by FNAC and to study the accuracy of cytological diagnosis against histopathological diagnosis. Methodology: In this cross-sectional study, 777 cases of clinically suspected nodular skin & subcutaneous lesions were studied by FNAC and 381 cases were additionally diagnosed histologically. Observations: Non-neoplastic lesions (45.03%) contributed the most, followed by benign (39.6%) and malignant tumours (15.37%). Total 377 out of 381 cases showed good correlation between cytology and histopathology (diagnostic accuracy-98.95%). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC in the diagnosis of malignancy were calculated to be 100%, 99.48%, 97.61% and 100% respectively. Conclusion: Cytodiagnosis by FNAC is a reliable screening technique in the evaluation of cutaneous and subcutaneous lesions.
ABSTRACT
Fine needle aspiration cytological features of solid-cystic tumor (SCT) of pancreas occurring adjacent to pancreas is reported for its rare occurrence. On cytology, diagnosis of paraganglioma was suggested. After histologic diagnosis of SCT, cytology was reviewed that showed typical features of SCT. On cytology, diagnostic problem in SCT occurring outside pancreas is illustrated.