ABSTRACT
Background: Sarcoidosis is a rare systemic granulomatous disorder with unknown cause. It is rare in the world and Vietnam. Objective: To study clinical, subclinical manifestations and therapy of sarcoidosis in Department of Respiratory of Bach Mai Hospital. Subjects and method: A study included 14 patients in Department of Respiratory of Bach Mai hospital, from 1989 to August 2006. This was a retrospective, descriptive study. Results and conclusions: In 14 patients, 14 patients (78.6%) was females, 3 (21.4%) was males. The disease occurred common in the ages of 20-49 years (85.7%). The clinical symptoms were very multiform but pulmonary symptoms were the most manifestations (78.6%). Abnormalities on chest radiographs were 92.8%, with stage 0 (7.1%), stage 1 (57.2%), stage 2 (28.6%), stage 3 (7.1%). Histopathologically, injuries of the sarcoidosis were typical in 9 patients (64.3%). The corticoid therapy satisfied the most success in 92.8% of patients. The side effects of the treatment occurred in 4 of 12 patients.