ABSTRACT
Abstract: Retronychia is a recently described disorder caused by ingrowth of the proximal nail plate into the proximal nail fold. It is suspected when there is persistent paronychia, particularly in the setting of trauma. This disease is probably underdiagnosed due to limited knowledge among dermatologists and the presence of incomplete clinical forms. Nail plate avulsion is the diagnostic and curative procedure of choice, despite reports of relapse.
Subject(s)
Humans , Nail Diseases/diagnosis , Paronychia/etiology , Onycholysis/complications , Nail Diseases/therapy , Nails, Ingrown/complicationsABSTRACT
Abstract: Fabry disease is a rare lysosomal storage disorder, inherited in an X-linked manner. It is characterized by the deficiency of the enzyme alpha-galactosidase, leading to a buildup of glycosphingolipids in the cells. Angiokeratoma is one of the cutaneous manifestations of this condition, and it helps making the diagnosis. The typical site involves the genital area in men and lumbosacral, buttocks and trunk region in both sexes. We report a case of genital angiokeratoma in a woman with Fabry disease. The diagnosis is through molecular analysis and, when made early, starting treatment reduces the morbidity and mortality of the disease. Thus, the dermatologist has an important role in the identification of angiokeratoma as a cutaneous marker, and the knowledge of its different presentations is essential for the early diagnosis and management of Fabry disease.
Subject(s)
Humans , Female , Middle Aged , Skin Neoplasms/diagnosis , Vulvar Neoplasms/diagnosis , Fabry Disease/diagnosis , Angiokeratoma/diagnosis , Physician's Role , Skin Neoplasms/pathology , Vulvar Neoplasms/pathology , Diagnosis, Differential , Enzyme Replacement Therapy , Dermatologists , Angiokeratoma/pathologyABSTRACT
Abstract: Acquired fibrokeratoma is a rare benign skin tumor that usually manifests as a slow-growing solitary nodular lesion of the digits. We report a case of plantar acquired fibrokeratoma evidencing its atypical size and topography, in addition to the treatment with simple surgical excision followed by healing by second intention. Nondigital fibrokeratomas may occur in 18% of cases and rarely affect the palmoplantar region. These lesions are usually asymptomatic and show ≥ 3cm in size at the time of diagnosis due to delayed diagnosis. Complete surgical excision is the treatment of choice, which is usually curative. In general, primary closure is chosen; however healing by second intention becomes an option in regions of difficult approach.
Subject(s)
Humans , Male , Middle Aged , Neoplasms, Fibroepithelial/surgery , Foot Diseases/surgery , Keratosis/surgery , Treatment Outcome , Neoplasms, Fibroepithelial/pathology , Wound Closure Techniques , Foot Diseases/pathology , Keratosis/pathologyABSTRACT
A hipercurvatura transversa é deformidade da placa ungueal, inestética e dolorosa, provocando desconforto ao paciente. O tratamento pode ser conservador ou cirúrgico. Dos conservadores a colocação da lâmina plástica de memória sobre a placa ungueal, utilizando cola de cianocrilato, promove rápida melhora da dor e seu alargamento entre três e seis meses. O uso de acelerador de cianoacrilato facilita o procedimento tornando-o mais rápido.
Transverse hypercurvature is a deformity of the nail plate, unaesthetic and painful, causing discomfort to the patient. Treatment can be conservative or surgical. Related to the conservative treatments, placing the flexible plastic blade on the nail plate using cyanoacrylate glue, promotes rapid improvement of pain and its widening from three to six months. The use of cyanoacrylate accelerator facilitates the procedure, making it faster.
ABSTRACT
Abstract: Mycological examination is still the cornerstone for the diagnosis of onychomycosis for many dermatologists, but sampling technique interferes on its sensitivity and specificity. Nail abrasion may be used to reach the most proximal part of the lesion and can be easily accomplished with an electric abrasor. We suggest nail plate dermoscopy to identify the best location for localized abrasion to obtain adequate samples for mycological examination.
Subject(s)
Female , Humans , Middle Aged , Dermoscopy/methods , Foot Dermatoses/pathology , Nails/pathology , Onychomycosis/pathology , Fungi/isolation & purification , Reproducibility of Results , Sensitivity and SpecificityABSTRACT
Abstract The Iso-Kikuchi Syndrome is a rare condition characterized by nail dysplasia involving the index fingers, including micronychia, polyonychia, anonychia, irregular lunula, malalignment and hemionychogryphosis. On the antero-posterior image, radiologic examination reveals a narrowing of the distal phalanx. The lateral image shows a Y-shaped bifurcation of the distal phalanx. We report a case of a patient with typical clinical and radiologic signs of Iso-Kikuchi Syndrome.
Subject(s)
Humans , Male , Adolescent , Finger Phalanges , Nails, Malformed , Syndrome , Radiography , Rare Diseases/congenital , Rare Diseases/diagnostic imaging , Finger Phalanges/abnormalities , Finger Phalanges/diagnostic imaging , Fingers/abnormalities , Fingers/diagnostic imaging , Nails, Malformed/congenital , Nails, Malformed/diagnostic imagingABSTRACT
A sixty-one year old white female was referred to the Dermatology Department to treat an ingrown nail in the inner corner of the left hallux. Examination of the entire nail unit showed the presence of xanthonychia in the outer corner besides thickening and increase in the transverse curvature of the nail plate. Dermoscopy and nuclear magnetic resonance of the free edge of the nail plate detected characteristic signs of onychomatricoma, a diagnosis that was later confirmed by anatomopathological exam.
Subject(s)
Humans , Anticholesteremic Agents/therapeutic use , Cholesterol Ester Transfer Proteins/antagonists & inhibitors , Fibric Acids/therapeutic use , Lipoproteins, HDL/blood , Niacin/therapeutic use , Coronary Disease/blood , Coronary Disease/mortality , Coronary Disease/prevention & control , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Myocardial Infarction/blood , Myocardial Infarction/mortality , Myocardial Infarction/prevention & control , Oxazolidinones/therapeutic use , Quinolines/therapeutic use , Randomized Controlled Trials as Topic , Stroke/blood , Stroke/mortality , Stroke/prevention & control , Sulfhydryl Compounds/therapeutic useABSTRACT
BACKGROUND: Superficial mycoses are fungal infections limited to the outermost layers of the skin. Dermatophytic filamentous fungi and yeasts are the major causative agents of these mycoses. Dermatophytosis is one of the clinical conditions caused by fungal infections most commonly found in dermatological practice. Thus, knowledge of the ecology of dermatophytes provides a better understanding of the natural history of dermatophytosis. OBJECTIVE: This study aimed to investigate epidemiological and mycological features of superficial mycoses diagnosed from 2005 to 2011 in the Dermatology Clinic of the Hospital do Servidor Público Municipal de São Paulo, Brazil. METHOD: This retrospective study was conducted in the Laboratory of Medical Mycology at the Dermatology Clinic of the Hospital do Servidor Público Municipal de São Paulo. Mycological examinations of 9042 patients with clinical suspicion of superficial mycoses performed between 2005 and 2011 were reviewed. RESULTS: Of 9042 direct microscopic examinations, 2626 (29%) were positive for dermatophytes, 205 (2.3%) were positive for Malassezia, 191 (2.1%) were positive for other types of yeast, 48 (0.5%) were positive for bacteria, and 5972 (66%) were negative. Mean age of patients was 48 years, 6920 (77%) patients were female and 2112 (23%) were male. CONCLUSION: The biota consisted of six dermatophyte species: T. rubrum, T. mentagrophytes, M. gypseum, T. tonsurans, E. floccosum, and M. canis. The most common site of involvement was the nail and foot in adults and scalp in children, with a female predominance. Both Candida and Malassezia were more prevalent in adult women, the former most commonly affecting the interdigital region and nails and the latter the chest and neck. .
Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Middle Aged , Young Adult , Dermatomycoses/epidemiology , Hospitals, Public/statistics & numerical data , Age Distribution , Brazil/epidemiology , Nails/microbiology , Prevalence , Retrospective Studies , Sex Distribution , Skin/microbiology , Yeasts/isolation & purificationABSTRACT
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Young Adult , Dermatology/statistics & numerical data , Foot Dermatoses/epidemiology , Hand Dermatoses/epidemiology , Onychomycosis/epidemiology , Onychomycosis/therapy , Brazil/epidemiology , Comorbidity , Exercise/physiology , Foot Dermatoses/diagnosis , Foot Dermatoses/microbiology , Foot Dermatoses/therapy , Hand Dermatoses/diagnosis , Hand Dermatoses/microbiology , Hand Dermatoses/therapy , Onychomycosis/diagnosis , Prevalence , Risk FactorsABSTRACT
Os autores relatam sua experiência no uso da dermatoscopia na psoríase ungueal e descrevem os achados dessa ferramenta diagnóstica.
The authors report on their experience with the use of dermoscopy in nail psoriasis and describe their findings with this diagnostic tool.