ABSTRACT
Background: Spinal induced maternal hypotension is a common problem during cesarean delivery. Timing of infusion of crystalloid may be important because of its short stay in intravascular space. Aim: This study was conducted to compare effectiveness of preloading and co-loading with crystalloid in prevention of spinal anesthesia induced maternal hypotension during caesarean section. Material and Methods: In total 62 parturients were randomized to two groups. Preload group (Group P) received 15 ml/kg of Ringer Lactate solution over 20 min before giving low dose (2 ml, 0.5% hyperbaric Bupivacaine) spinal anesthesia and coload group (Group C) were given same volume of Ringer Lactate solution as fast as possible after CSF tapping and Bupivacaine injected. Non-invasive BP measurements were recorded. The incidence of hypotension and dose of inj. Mephentermine were checked. Blood pressure, heart rate, nausea and neonatal outcome were assessed. Results: The incidence of hypotension, blood pressure drop and dose of Mephentermine was lower in the coload group compared to the preload group (significant p<0.05). The incidence of nausea was also lower in the coload group. No significant differences in neonatal outcome. Arpit Singhal, Ashima Gupta, S.P. Chittora. Influence of the timing of administration of crystalloid on maternal hypotension during low dose spinal anesthesia for elective cesarean delivery: Preload versus coload. IAIM, 2019; 6(5): 16-21. Page 17 Conclusion: In case of using crystalloids (ringer lactate) for cesarean delivery, coload is more effective than preload for the prevention of maternal hypotension after spinal anesthesia for caesarean delivery.