ABSTRACT
A total of 424 blood samples were collected from two distinct populations. Local agricultural group and migratory industrial workers of West Bengal were compared with respect to haemoglobin, ABO and Rh systems. There was absence of any significant genetic difference in case of haemoglobin system.
Subject(s)
ABO Blood-Group System/genetics , Adult , Developing Countries , Gene Frequency/genetics , Genetics, Population , Hemoglobin A/genetics , Hemoglobin A2/genetics , Hemoglobin E/genetics , Hemoglobins, Abnormal/genetics , Humans , India , Middle Aged , Rh-Hr Blood-Group System/genetics , Rural Population , Transients and MigrantsABSTRACT
Retrospective study was carried out in 1,15,851 consecutive births in five hospitals, and prospective study of 10,415 consecutive births in one hospital of West Bengal. The overall frequency of congenital defects was 4.42/1000 live births. Incidence of NTD and talipes was predominant in rainy season, whereas cleft palate with/without hare lip had highest frequency during winter. Incidence of these anomalies decreased with increasing birth order. The frequency was noted to decline with increasing maternal age, 21-25 years age group had maximum number of malformed babies. Sex ratio and religion, however, did not have any correlation with the incidence of these malformations. When comparison was done between urban and rural population no statistically significant variation was observed.