Agenesis of the dorsal pancreas (ADP) and pancreatitis - is there an association?

Agenesis of the dorsal pancreas (ADP) is a rare congenital anomaly. We describe four patients with ADP presenting with acute pancreatitis. One patient had diabetes mellitus and another had malrotation of duodenum as an additional feature. All patients improved on conservative management.

Rome I criteria are more sensitive than Rome II for diagnosis of irritable bowel syndrome in Indian patients.

AIM: To assess the utility and efficacy of Rome I and Rome II criteria for the diagnosis of irritable bowel syndrome (IBS) in India. METHODS: Patients referred with a diagnosis of IBS by general practitioners answered a questionnaire about clinical features, including those listed in the Rome I and Rome II criteria. All patients underwent investigations to determine the cause of their symptoms. Sensitivity, positive predictive value and percent agreement of final diagnosis with Rome I and II criteria were calculated. RESULTS: Among 138 patients studied, 6 patients had organic disease . Amongst 132 patients with functional bowel disease, Rome I criteria diagnosed more patients as IBS than Rome II criteria (110 [83.3%] vs. 41 [31.1%]); 36 patients fulfilled both the criteria. Of the patients positive by Rome I, 32.7% fulfilled Rome II criteria, and of those diagnosed by Rome II criteria, 87.8% fulfilled Rome I criteria. Seventeen patients did not fulfill either Rome I or Rome II criteria, and were classified as functional abdominal bloating, functional diarrhea or functional constipation. CONCLUSION: Rome I criteria are more sensitive than Rome II criteria for the diagnosis of IBS in the Indian population.