The tuberculin test in children after BCG immunization

We conducted tuberculin test with tuberculin 2UI 0,1ml PPD 23 Tween 80 by Copenhagen among 250 children who had BCG immunization after 3 months. The results of study: the positive rate of tuberculin test was 62%, 51.2% diameter of positive reaction was 6-10 mm. The positive rate of tuberculin test among the children who had breast feeding was higher among the rest group children (65.8% vs. 51.5%). Age of children when injection (during the first three months), weight of birth, a way of delivery did not influence to the positive rate of tuberculin test.

Clinical development in the children after BCG immunization

The study was conducted among 400 children with age of 1-90 days who were healthy at birth without acute disease during Aug-Oct, 2000. The children were BCG immunization, 0.05 mmg 286A seri by Nha Trang vaccine institute in Oct, 1998. The result of study: Symptoms of the children after BCG immunization included fever in the first day after BCG immunization (0.3%), physical strength of the children developed in normal progress (increasing average 2.7  0.9 kg during 3 months), 0.75% of the children had lymph nodes in left arm with average size 2.5 cm. The nodes disappeared after 3 months without any treatment. 10.5% of the children had diarrhea, bronchitis. At the location of BCG injection: 6.3% of the children without any symptoms. 11.2% of them had red node only. After 2 months of injection, ulcer 82.5%. It developed a scar during 2 weeks with diameter 2.29  0.82 mm.