1.
Medical Journal of Chinese People's Liberation Army
;
(12): 1077-1080, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-849629
ABSTRACT
Cardiovascular disease is currently the number one killer of human health. Studies have shown that peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a key factor in physiological processes such as energy metabolism and oxidative stress, which also involved in regulating mitochondrial biosynthesis. PGC-1α is closely related to the occurrence and development of atherosclerosis, coronary heart disease, atrial fibrillation, cardiomyopathy, myocardial hypertrophy, heart failure and other cardiovascular diseases. This article briefly describes the research progress of PGC-1α in cardiovascular diseases.