ABSTRACT
Head and cervical artery dissections refer to destruction of integrity of the wall of extracranial carotid artery, extracranial vertebral artery and intracranial artery. In arterial dissection, blood enters the cleft between intima and media or the cleft between intima and adventitia of arterial wall, becoming intramural hematoma. Head and cervical artery dissections are among the most common causes of stroke in young people. The etiology, pathogenesis, diagnosis and treatment of head and cervical artery dissections were reviewed in this article, aiming to provide reference for clinical practice.
ABSTRACT
Experimental autoimmune encephalomyelitis ( EAE ) is a classic animal model for multiple sclerosis . After more than 2 centuries of development , EAE can be established in mice , monkeys and rats ,etc.Some animals can be immunized by different immune antigens which have different features in sensibility and clinical characteristics .In this pa-per, we will review the development of EAE , discuss the characteristics of EAE models produced by immunization of differ-ent animals with different antigens .In summary, we explore the development of animal models of EAE .