ABSTRACT
Acute pancreatitis in pregnancy is a rare but serious disease, and its incidence has shown a significant upward trend in recent years. Due to the progress of diagnosis and treatment technology, the maternal and infant mortality caused by this disease has decreased. However, it is still a great threat to the health of mothers and infants because of its acute onset, many complications, atypical clinical manifestations and difficulties in diagnosis.Therefore, early diagnosis and standardized treatment are the key to reduce the harm to pregnant women and fetuses. This article will review the epidemiology, etiology, diagnosis and treatment of acute pancreatitis in pregnancy.
ABSTRACT
Preeclampsia is one of the main causes of high morbidity and mortality of pregnant women and perinatal infants worldwide. Affected by many factors, preeclampsia has a complex pathogen-esis and can cause involvement of multiple organs and systems. Its pathogenesis is still unclear. Current research suggests that maternal immune system indirectly involved in the pathophysiology of preeclampsia change, that is, abnormal activation of innate immune cells and unbalanced differentiation of T helper cell subsets interfere with normal immune regulation, and interact with inflammatory response of the body, which produces cytotoxic environment at the maternal-fetal interface and affects trophoblast inva-sion. Therefore, clarifying the role of the immune system can not only clarify the pathogenesis of pre-eclampsia, but also contribute to the development of diagnosis and treatment of preeclampsia. This paper reviews the research status of immune system in preeclampsia, including innate immunity and adaptive immunity . The immune mechanism of preeclampsia is elaborated mainly from immune regulation mediated by T lymphocyte, natural killer ( NK) cell, macrophage and human leukocyte antigen.