ABSTRACT
Se presenta un caso de leiomioma pulmonar metastizante en una mujer de 48 años. El estudio histológico reveló múltiples nódulos pulmonares de musculatura lisa de aspecto benigno. El seguimiento a 8 años mostró una paciente en buenas condiciones generales sin síntomas respiratorios. La historia clínica reveló antecedentes de histerectomía cuatro años antes debido a múltiples leiomiomas. Se hace una revisión clínico patológica de los tumores musculares lisos uterinos en sus formas clásicas y en sus presentaciones inusuales.
A case of pulmonary benign metastasizing leiomyoma in a 48 years old female is presented. The histological study showed pulmonary nodules formed by smooth muscle cell of benign appearance. The 8 years follow up revealed a patient in a good fashion without respiratory symptoms. There was a 4 years history of previous hysterectomy due to multiple uterine leiomyomas. A clinico pathological review of the classical and unusual forms of smooth muscle tumors of the uterus is also presented.
Subject(s)
Middle Aged , Leiomyoma/pathology , Lung Neoplasms/secondary , Uterine Neoplasms/pathology , Multiple Pulmonary Nodules/secondaryABSTRACT
Ocasionalmentes luego de una histerectomía simple, aparece un cáncer de cuello uterino (CCU) como hallazgo incidental (CIC) a la Anatomía Patológica (AP). Esta entidad, es de alto riesgo de recidiva locorregional, por lo que requiere de un tratamiento complementario. Propósito: analizar retrospectivamente los resultados de Radioterapia (RTX) complementaria en mujeres con diagnóstico de CIC referidas al Hospital Las Higueras (HH) y Centro Onco-Radiológico Regional (CORR) y compararlos con similares a comunicados en la literatura. Se analizan 29 pacientes con diagnóstico de CIC, referidos a HH y CORR entre agosto 1988 y junio 2000, tratados complementariamente con radioterapia externa y/o intracavitaria. La sobrevida actuarial a 5 años fue de 86%. El control locorregional actuarial de la totalidad de la muestra fue de 86%. En 5/29 pacientes fallecidas, todas de CCU. De las 5 fallas a tratamiento, 4 con falla locorregional. Una, con histología carcinoma indiferenciado de células pequeñas, con control locorregional y falla distante a los 175 meses. La RTX complementaria es altamente efectiva en el tratamiento de CIC.
Twenty nine patients with proven invasive cervical cancer found after simple hysterectomy were treated with complementary external and/or intracavitary Radiotherapy, 5 year actuarial survival rate of 86%. Local and regional control was achieved in 25/29, 83%. One patient presented with a complication grade 2, no treatment related deaths.
Subject(s)
Humans , Female , Adult , Middle Aged , Aged , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/radiotherapy , Incidental Findings , Hysterectomy , Survival Analysis , Uterine Cervical Neoplasms/surgery , Retrospective Studies , Follow-Up Studies , Treatment Outcome , Radiotherapy, AdjuvantSubject(s)
Adolescent , Adult , Middle Aged , Humans , Male , Female , Leukemia, Promyelocytic, Acute/complications , Disseminated Intravascular Coagulation/complications , Fibrinolysis , Thrombocytopenia/complications , Fibrin Fibrinogen Degradation Products/analysis , Fibrinogen/analysis , Heparin/therapeutic use , Leukemia, Promyelocytic, Acute/blood , Cerebral Hemorrhage/mortality , Cerebral Hemorrhage/drug therapy , Antifibrinolytic Agents/therapeutic useABSTRACT
Myelodysplasia, characterized by varied reductions of peripheral blood elements with normal or hypercellular bone marrow, is reltively frequent among older patients and may evolve to acute leukemia. We reviewed findings in 35 patients whon, according to the FAB classification were distributed as follows: simple refractory anemia (RA) 34%, sideroblastic refractory anemia (SRA) 14%, refractory anemia with excess blast forms (RAEB) 31%, chromic myelomonocytic leukemia (CMML) 12% and refractory anemia eith excess blast forms in transformation (RAEBT 9%). Cytogenetic studies performed in 16 patients were abnormal in 5(31%), al among patients with poor prognosis forms of the disorder. All patients had anemia; thrombopenia and neutropenia were more frequent in subtypes RAEB, CMML and RAEBT). Mean survival rate was 30 months, significantly greater in RA and SRA comapred to the other groups. Infections and development of acute leukemia were the causes of death