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Chinese Journal of Stomatology ; (12): 292-294, 2010.
Article in Chinese | WPRIM | ID: wpr-245205

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the short-term results and safety of propranolol for the treatment of infantile parotid hemangioma.</p><p><b>METHODS</b>Oral propranolol was administered to 17 infants with parotid hemangioma at a dose of 1.0-1.5 mg per kilogram of body weight per day. The patients were revisited once a week. The changes of the tumor size, texture and colour were monitored and recorded at a regular interval. The adverse effects after medication were observed and managed accordingly. The short-term results were evaluated using a 4 scales system.</p><p><b>RESULTS</b>Among the 17 patients treated, the follow-up time was 5 to 10 months. The overall response was scale I in 0 patient, scale II in 0 patients, scale III in 5 patients, and scale IV in 12 patients. No serious adverse effects were encountered.</p><p><b>CONCLUSIONS</b>Oral propranolol at a lower dose is a safe and effective method for the treatment of infantile parotid hemangioma. The short-term results were excellent and the side effects minimal.</p>


Subject(s)
Female , Humans , Infant , Male , Administration, Oral , Adrenergic beta-Antagonists , Therapeutic Uses , Follow-Up Studies , Hemangioma , Drug Therapy , Parotid Neoplasms , Drug Therapy , Propranolol , Therapeutic Uses , Treatment Outcome
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