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Journal of Forensic Medicine ; (6): 9-11, 2002.
Article in Chinese | WPRIM | ID: wpr-982919

ABSTRACT

OBJECTIVE@#To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection.@*METHODS@#Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphine poisoning by immunohistochemical SP method.@*RESULTS@#Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found.@*CONCLUSION@#The kidney and brain may be the ideal organs for sampling in suspected morphine poisoning cases with.


Subject(s)
Adult , Female , Humans , Male , Brain/metabolism , Forensic Medicine , Immunohistochemistry , Kidney/metabolism , Morphine/poisoning , Morphine Dependence/metabolism , Tissue Distribution
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