A Case of Acute Hhperpyrexia during Diethyl Ether Anesthesia: A Case report / 대한마취과학회지

The authors have experienced a case of acute hyperpyrexia with convulsion during diethyl ether anesthesia, which is rare and its etiology not well known.

Clinical Evaluation of Fluothane Anesthesia for Cesarean Section / 대한마취과학회지

In 97 cases of uncomplicated Cesarean section proceeding under 0.5% fluothane anesthesia with N2O and O2, 2.5% Pentothal sedium(clinical induction doses) was enough until umbilical cord clamp without any supplemental doses but muscle relaxation from succinylcholine might not be potentiated with 0.5% fluothane. On the other hand, Apgar score and postpartum uterine contractility was depending upon duration of anesthesia but it was not so serious problem. Also, anesthesia induction and recovery was rapid, and post operative pulmonary and other complication, even vomiting, did not occur. Conclusively, it is interesting that low concentration of fluothane with nitrous oxide are probably ideal anesthesia method for Cesarean section.

Antimycobacterial Activities of Dodecyl diaminoethyl glycin hydrolchloride as a Disinfectant / 대한마취과학회지

In order to prevent cross-infection, the sterilization of used and/or contaminated anesthetic- apparatus is still a difficult problem in clinical practice, particularly, following anesthesia for known advanced pulmonary tuberculosis cases. Therefore the antibacterisl activities of, an amphoteric detergent, Dodecyl diaminoethyl glycin hydrochloride (Hygien 51) were tested in vitro as a disinfectant against mycobacteria (M. tuberculosis H37 Rv, M. bovis, M. avium, M. tuberculosis H37 Ra, M. phlei, B.C.G.) The antimycobacterial activity tests were performed according to the modified Kolmer method. The testing organisms were cultured in Dubos broth at 37 degrees C, and the detergent, Hygien 51, was: diluted with sterile distilled water to 1,3,5 and 10%. One half milliliter of culture was pipetted into each tube containing 4.5 ml of diluted detergent, and at intervals of 3, 15, 30, 60, 120, 180 and 240 minutes, a 4mm loopful of the material was removed from each tube, and transferred to Ogawa media. The tests were carried out at two different temperatures, 20 degrees C and 50 degrees C. The subcultures were incubated at 37 degrees C for more than 8 weeks. The results were obtained as follows: 1) At room temperature (20 degrees C), all mycobateria, except M. bovis, were destroyed by treatment- with 10% solution of the detergent for more than 60 minutes. M. bovis was relatively sensitive to the detergent, and was killed by 5% solution for 30 min. and 10% for 15 min., but M. avium. was very resistant, and was not killed by 10% solution for 240 min. 2) By treatment with the detergent at 50 degrees C, the antimycobacterial activities of the detergent were highly increased. All mycobacteria were destroyed by 1% solution for 180 min, and by 10% for less than 30 min at 50 degrees C. In the comparison of the antibacterial activities against mycobacteria and other bacteria, it shows that mycobacteria are generally more resistant to the detergent, Hygien 51.

Clinical Evaluation of Electro-convulsive Therapy under the General Anesthesia / 대한마취과학회지

In 1938 Cerletti described a method of producing convulsions by eleetricity and began its use in the treatment of schizophrenias. In avoider to avoid fractures or dislocation and to diminish the risk, convulsion may be modified by means of drugs which inhibit the action of acetylcholine at neuro-muscular junctions and often the muscular contractions combining ultra short acting barbiturate especially thiopental sodium. Since ultra short acting barbiturat, like thiopental, require postanesthesia supervision of the patient for up to an hour, the recentlyintroduced ultrashort-acting nonbarbiturate anesthetic agent, propanidid, was investigated for comparison with thiopental sodium. One hundred psychiatric patients under the diognosis of involutional melancholia, manic depressive psychosis, schizophrenia and neurotic depression, divided into two equal groups, were subjected to electroconvulsive therapy by thiopental-succinylcholine (Group 1) and propanidid-succinyl choline (Group 2). In our study, there were no definite change in blood pressure and heart rate after electroconvulsive therapy in both group. Duration of apnea in Group 2 averaged 63 seconds longer than in Group 1, but awakening and ambulation averaged 5 minutes and 40 minutes shorter than in Group 1. Complications after E.C.T. were minimal and not significant different between two groups.

Intravenous Regional Anesthesia / 대한마취과학회지

Clinical experience using different anesthetic methods for intravenous regional anesthesia in extremities was compared, To group 1 (22 cases, 20 for upper extremity and 2 for lower extremity surgery, with 5 min. limb elevation) 1.5mg/kg Lidocaine hydrochloride was administered and a single pneumatic tourniquet applied. For both group 2 (15 patients, 10 for upper limb and 5 for lower limb operations with limb elevation) and group 3 (11 cases, all for upper extremity operations, but Esmarch bandages instead of pre tourniquet elevation) 3. 0 mg/kg Lidocaine hydroehloride was used and a second tourniquet placed distal to the first. In all groups the anesthetic concentration was 0. 5 and 0. 25 per cent for the upper and lower extremities respectfully. Pneumatic tourniquet pressure applied was 250 mmHg for the upper limb and 500mmHg for the lower. Excellent anesthesia resulted in 68. 2 per cent in group 1, 73.3 per cent in group 2, and 100 per cent in group 3. No serious complications were encountered. Incidence of incomplete anesthesia and/or tourniquet pain could be decreased by increasing the anesthetic concentration, using a secondary tourniquet, and by selecting the region to be anesthetized (upper extremities in favor of the lower). It is concluded that intravenous regional anesthesia is simple, effective and safe and is recommended for ambulatory patients, emergency operations and for patients for whom general anesthesia is deferred.