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Objective To study the clinical value of peripheral venous blood circulating tumor cell count in patients with non -small -cell lung cancer (NSCLC).Methods 28 patients with NSCLC were chosen as observa-tion group,at the same time,16 patients with benign lung tumor and 16 healthy persons were chosen as the control group 1,2.Before and after treatment,the peripheral venous blood circulating tumor cell counts were studied to under-stand its value in clinical.Results CK -FITC expression rate of adenocarcinoma patients was 95.8%,CD326APC expression rate was 94.5%,CK -FITC and CD326APC expression rate was 94.6%.CK -FITC expression rate of squamous carcinoma was 93.7%,CD326APC expression rate was 93.9%,CK -FITC and CD326APC expression rate was 94.1%,the differences between the two groups were not significant (χ2 =2.89,1.36,2.14,all P >0.05).The positive rate of peripheral venous blood circulating tumor cells in the observation group was significantly higher than the two control groups,and before treatment,the positive rate of peripheral venous blood circulating tumor cell was higher than after treatment.Conclusion Peripheral venous blood circulating tumor cell count can determine the dis-ease development process.
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Objective To investigate the influence and the efficacy for lipid level of rosuvastatin with atorv-astatin in the treatment of coronary heart disease.Methods 160 patients with coronary heart disease were randomly divided into the observation group and the control group,80 cases in each group.The patients of the observation group were given rosuvastatin 10mg every night,the control group were treated with the same dose of atorvastatin every night,the efficacy before and after treatment were compared after continuous 21d,and the lipid changed of the two groups were compared.Results There were statistically significant difference in the lipid level of the observation group before and after treatment(t =3.728,4.516,5.322,3.143,all P <0.05),and after treatment the TC,TG,LDL-C levels of the observation group were lower than those of the control group,the HDL -C level was higher than that of the control group,the difference was statistically significant(t =3.512,5.529,6.325,3.139,all P <0.05);There were statistically significant differences in hs -CRP,Hcy,IMT of the observation group before and after treatment [(14.35 ±1.56)μmol/L vs (22.45 ±1.82)μmol/L,(0.31 ±0.03)g/L vs (0.45 ±0.06)g/L,(1.64 ±0.11)mm vs (2.03 ±0.12)mm](t =3.728,3.231,3.452,all P <0.05),and the hs -CRP,Hcy,IMT of the observation group were lower than those of the control group[(14.35 ±1.56)μmol/L vs (16.56 ±1.26)μmol/L,(0.31 ±0.03)g/L vs (0.38 ±0.05)g/L,(1.64 ±0.11 )mm vs (1.81 ±0.12)mm](t =3.512,3.529,4.325,all P <0.05 ). Conclusion The treatment effect and lipid level of rosuvastatin was superior to atorvastatin.
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BACKGROUND: Craniofacial hard tissue structures vary in age, gender, regional and racial differences. Some researchers have conducted X-ray cephalometric measures of malocclusion deformity in some domestic cities, and obtained normal cephalometric measures of craniofacial hard tissue structure. However, little data have been available concerning cephalometric measures of craniofacial hard tissue structure of Tibetan youth in Tibet region. OBJECTIVE: To observe structural features of craniofacial hard tissue of permanent tooth occlusal period in the adolescent of Lhasa. DESIGN, TIME AND SETTING: Stratified cluster sampling survey was performed at Naqu, Tibet from June to August 2008. PARTICIPANTS: A total of 200 adolescents at permanent tooth occlusal period, 100 males and 100 females aged 11-14 years were selected from middle and primary schools of Lhasa in 2003. The inclusion criteria included: teeth in order, neutral occlusal adjustment, normal maxilla and mandible appearance and relationship, normal teeth number and overbite and overjet, concordant face, and no history of orthodontic management. METHODS: According to the requirements and standards for the irradiation, 200 subjects underwent X-ray cephalometric measures, and the results were compared with normal values of the same age. MAIN OUTCOME MEASURES: SNA angle, SNB angle, ANB angle, 1-SA angle, 1-NA angle, 1-NA, T-MP angle, Y axial angle, NP-FH angle, NA-PA angle, 1-T angle, MP-SN angle, Po-NB, T-NB angle, T-NB, and MP-FH angle. RESULTS: No significant differences were found between Lhasa adolescents and normal values in terms of SNA angle, SNB angle, ANB angle, 1-SN angle, 1-NA angle, 1-NA, T-MP angle, Y axial angle, NP-FH, NA-PA, 1-T, and MP-SN. Po-NB was slightly greater than normal value and T-NB angle, T-NB and MP-FH were significantly less than normal values. CONCLUSION: Lhasa adolescents have significantly different craniofacial hard tissue structure from normal values: forward protrusion of mental region, flat mandible angle, straight mandible anterior teeth, upward and forward rotated mandible, and straight face type.
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BACKGROUND:Craniofacial hard tissue structures vary in age,gender,regional and racial differences.Some researchers have conducted X-ray cephalometric measures of malocclusion deformity in some domestic cities,and obtained normal cephalometric measures of craniofacial hard tissue structure.However,little data have been available concerning cephalometric measures of craniofacial hard tissue structure of Tibetan youth in Tibet region.OBJECTIVE:To observe structural features of craniofacial hard tissue of permanent tooth occlusal period in the adolescent of Lhasa.DESIGN,TIME AND SETTING:Stratified cluster sampling survey was performed at Naqu,Tibet from June to August 2008.PARTICIPANTS:A total of 200 adolescents at permanent tooth occlusal period,100 males and 100 females aged 11-14 years were selected from middle and primary schools of Lhasa in 2003.The inclusion criteria included:teeth in order,neutral occlusal adjustment,normal maxilla and mandible appearance and relationship,normal teeth number and overbite and overjet,concordant face,and no history of orthodontic management.METHODS:According to the requirements and standards for the irradiation,200 subjects underwent X-ray cephalometric measures,and the results were compared with normal values of the same age.MAIN OUTCOME MEASURES:SNA angle,SNB angle,ANB angle,1-SA angle,1-NA angle,1-NA,?-MP angle,Y axial angle,NP-FH angle,NA-PA angle,1-? angle,MP-SN angle,Po-NB,?-NB angle,?-NB,and MP-FH angle.RESULTS:No significant differences were found between Lhasa adolescents and normal values in terms of SNA angle,SNB angle,ANB angle,1-SN angle,1-NA angle,1-NA,?-MP angle,Y axial angle,NP-FH,NA-PA,1-?,and MP-SN.Po-NB was slightly greater than normal value and ?-NB angle,?-NB and MP-FH were significantly less than normal values.CONCLUSION:Lhasa adolescents have significantly different craniofacial hard tissue structure from normal values:forward protrusion of mental region,flat mandible angle,straight mandible anterior teeth,upward and forward rotated mandible,and straight face type.
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60 kg) was given to all the patients 1-3 days after their operation.The pacing threshold and the amplitude of P and R waves on cardiograph were measured before injection and at 10,30,90,180 minutes afterwards.Results No significant changes were oburved in pacing threshold and the amplitade of P and R waves before and after the injection of metoprolol in patients with either newly implanted or replacement of permanent pacemakers.Conclusion Metoprolol tartrate has no effect on atrial and ventricular pacing threshold and the amplitude of P and R waves in patients with permanent pacemakers implantation.