ABSTRACT
Objective To investigate the present situation of facial melanin of construction workers in Beijing area,to discuss the relative affecting factors,and to provide theoretical basis for theoretical research on photoaging and occupational protection for construction workers.Methods A total of 157 healthy male construction workers and 61 non-construction workers in Beijing were selected to conduct a questionnaire survey on their exposure to dust,sunlight,noise and high temperature in their working environment.The occurrence of melanin in their face skin was measured by melanin index (melanin index,MI) probe.T test,Spearman rank correlation analysis and multiple logistic regression were used for statistical analysis on two independent samples.Results The exposure of construction workers to dust,sunlight,noise and high temperature was significantly higher than that of non-construction workers (P ＜0.05);the melanin score of construction workers over 40 years old was significantly higher than that of non-construction workers (P ＜0.05) and positively correlated with age (P＜0.05);the melanin of construction workers was affected by age,sunlight and noise (P＜0.05).Conclusions The melanin level of the construction workers aged over 40 is significantly higher than that of the non-construction workers in Beijing.Age,sunlight and noise are the main factors affecting the melanin level.
ABSTRACT
Objective To study the mechanism of Qingre Huashi Yiqi Huoxue Formulae (Formulae for clearing heat,dissolving damp,reinforcing qi and activating blood) for H.pylori associated gastric diseases. Methods The 70 C57BL/6 mice were randomly divided into 7 groups with 10 in each:normal group,model group,Chinese medicine high,medium and low dosage groups,western medicine group,and the combination of Chinese and western medicine group. Ampicillin combined with H.pylori gavage was adopted to produce H.pylori infected models. Four weeks later,all the groups were given correspondent treatment. The morphological and pathological changes of the gastric mucosa and the colonization of H.pylori in the gastric mucosa were observed after 2 weeks. ResultsThe Chinese medicine high and medium dosage groups and the combination of Chinese and western medicine group had a better effect in clearing H.pylori (P0.05). The Chinese medicine high and medium dosage groups,western medicine group,and the combination of Chinese and western medicine group had a significant morphological changes (P