ABSTRACT
Objective To observe the clinical effect of Bazhen decoction Huaji pill combined with transcatheter arterial chemoembolization ( TACE) in the treatment of primary liver cancer. Methods From December 2016 to October 2017,76 patients with primary liver cancer admitted to the People's Hospital of Haiyang were selected. According to the different clinical treatment methods,the patients were divided into two groups,with 38 cases in each group. The control group received hepatic arterial chemoembolization, and the observation group received Bazhen decoction Huaji pill combined with TACE. Results The total remission rate of the patients in the observation group was 63. 16％ (24/38),which was significantly higher than 23. 68％(9/38) in the control group (χ2 =12. 050,P<0. 05). The improvement rate and stability rate of KPS score in the observation group were 47. 37％(18/38),36. 84％(14/38),respectively,which were higher than those in the control group [26. 32％(10/38),31. 58％(12/38),χ2 =6. 397,P<0. 05]. The incidence rate of adverse reactions in the observation group was 21. 05％,which was lower than 44. 74％ in the control group,the difference was significant(χ2 =4. 828,P<0. 05). Conclusion Bazhen decoction Huaji pill combined with TACE in the treatment of patients with primary liver cancer can effectively alleviate the patients'condition,improve the quality of life of patients,and has high safety. It is worthy of popularization and application.
ABSTRACT
Objective To observe the effect of Lidan decoction combined with magnesium isoglycyrrhizinate in the treatment of liver injury after radiofrequency ablation(RFA) for liver cancer. Methods From February 2015 to February 2016,60 liver cancer patients with liver injury after RFA in the People＇s Hospital of Haiyang were selected in this study. The patients were randomly divided into the observation group and control group,with 30 cases in each group. The observation group was given Lidan decoction combined with magnesium isoglycyrrhizinate,and the control group was given conventional therapy. Results After treatment,the total effective rate of the observation group was 90. 00% (27/30),which was higher than 66. 67% (20/30) of the control group (χ2=4. 811,P＜0. 05). The levels of albumin (ALB),direct bilirubin (DBIL),AST,ALT in the observation group were (39.02 ±0.91)g/L,(6.31 ± 0.71)μmol/L,(59.12±5.81)U/L,(54.18±8.31)U/L,respectively,the differences were statistically significant between the two groups (t=7. 199,6. 211,6. 440,7. 928,all P＜0. 05). Conclusion Lidan decoction combined with magnesium isoglycyrrhizinate is effective in treating liver cancer patients with liver injury after RFA.
ABSTRACT
Objective To observe the clinical efficacy of Yishen Huayu Decoction for decreased ovarian reserve (DOR). Methods Eighty cases of DOR were randomly divided into 2 groups, with 40 cases in each group. The treatment group was treated with oral administration of Yishen Huayu Decotion, one dose a day. The control group was given DHEA, a time of 1 tablet, 3 times a day. 2 groups were observed for 3 menstrual cycles. The levels of basic follicle stimulating hormone (bFSH), basal estradiol (bE2), luteinizing hormone (LH) and serum anti-Müllerian hormone (AMH) were measured. The number of basal follicles and the peak systolic velocity (PSV) were monitored by transvaginal sonography. Quality of life assessment and basal body temperature were measured. Results The total effective rate was 85.00% (34/40) in the treatment group and 62.50% (25/40) in the control group, with statistical significance (P<0.05). After treatment, the levels of bE2 and bFSH decreased, and the levels of AMH, ovarian antral follicles and PSV increased, which were significantly different from those before treatment (P<0.05). After treatment, the levels of bE2 and bFSH in the treatment group were lower than those in the control group, and the levels of AMH, ovarian antral follicle and PSV were higher than those in the control group, with statistical significance (P<0.05). The recovery rate of basal body temperature was 77.50%(31/40) in the treatment group and 52.50%(21/40) in the control group, with statistical significance (P<0.01). After treatment, the scores of four dimensions of life quality, daily activities, health status and self-perception were significantly improved (P<0.01), and the treatment group was higher than the control group (P<0.01). Conclution Yishen Huayu Decotion can improve the ovarian reserve function and the life quality of patients with DOR.