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Rev. argent. reumatol ; 24(2): 46-48, 2013. ilus
Article in Spanish | LILACS | ID: lil-724418

ABSTRACT

El interferon (IFN) es una citoquina producida por distintas poblaciones de células y, a partir de su estructura, se han desarrollado varias drogas biológicas utilizadas en un amplio espectro de enfermedades. Se han descripto lesiones cutáneas y casos de síndrome de Raynaud severo con gangena digital co IFN alfa y beta. En este reporte presentamos una paciente con necrosis digital asociada a la administración de IFN beta


Interferon (IFN) is a cytokine produced by different immune competentcells and, based on its structure, several IFN biologic drugs and are now used as treatment for a wide spectrum of diseases. There are reports of cutaneous side effects and cases of severe Raynaud ́s syndrome with digital gangrene especially with both alpha and beta IFN. We report a patient who developed digital necrosis associated with beta Interferon.


Subject(s)
Interferon-beta , Necrosis , Vasculitis
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