Use of bleomycin sulfate in treatment of keloidal scars

Keloidal scars may be clinically and/or surgically treated; however, drugs or surgical procedures do not prevent or cure the scars. The author used intralesional injections of bleomycin as a new treatment. The histopathological examination performed before and after infiltrations demonstrates the beneficial effect ofbleomycin, confirmed by the clinical progression of the lesions. The study was carried out with 15 patients treated at the Plastic Surgery Service of Clementino Fraga Filho Teaching Hospital - Universidade Federal do Rio de Janeiro, from February 1998 to March 2000.