ABSTRACT
Objective To explore the role of endogenous and exogenous β-glucuronidase( β-G) in the development of primary common duct stones.Method Using modified Fishman method to test the activities of the endogenous and exogenous β -G in 35 patients with primary common duct stones(experimental group) and 11 patients with cystic polypus (control group) respectively.Results The activities of endogenous β -G in the bile of experimental group and control group were (7859.1 ± 738.5 ),(2174.9 ± 348.4 ) U/L(P ＜0.01).While the activities of exogenous β-G in experimental group and control group were (6786.1 ±544.3),(1504.7 ±655.7) U/L (P ＜0.01).In experimental group,there were significant statistical differences in the activities of the exogenous β -G in the sample obtained on the day of operation and 7 days after operation from 13 cases with the acute inflammation [(8935.7 ± 845.9),(2176.1 ± 956.7) U/L]and from 22 cases with the chronic inflammation [(5137.2 ±540.7),(1838.8 ±733.3) U/L],and there were significant higher in the activities of the exogenous β -G in the sample obtained on the day of operation from the acute inflammation compared to those from the chronic inflammation (P ＜ 0.05 ).Conclusions There is obvious correlation between either endogenous or exogenous β -G with primary common duct stones.And the endogenous β -G might be one of the fundamental cause in the development of primary common duct stones.
ABSTRACT
Objective To explore causes and preventive measures of recurrent laryngeal nerve injury during endoscopic thyroidectomy.Methods Clinical data of 3 cases of recurrent laryngeal nerve injury from 101 cases of endoscopic thyroidectomy in this hospital from January 2002 to July 2006 were retrospectively analyzed and summarized.Results There were 3 cases of hoarseness occurred at 24 h after operation.Under indirect laryngoscopy,the unilateral vocal cord was found immobile.The reasons leading to the injury included thermal burn by ultrasound knife in 2 cases and edema compression in 1 case.The injury was transient recurrent laryngeal nerve paralysis.The symptoms subsided spontaneously 3 months after operation in 2 cases and 20 days after operation in 1 case,respectively.Conclusions The recurrent laryngeal nerve injury is usually correlated with unskillful use of ultrasound knife.The improvement of surgeon's technique is crucial to reduce the incidence of this complication.