ABSTRACT
Odontogenic myxoma is a rare tumor, often diagnosed during routine radiographs or when it is so severe that it causes pain, a noticeable increase in volume or tooth displacement and mobility. Young adults (25-30 years of life) are more often affected by the lesion but all ages are vulnerable. The mandible is more commonly involved than the maxilla and the tumors usually grow slowly and silently. However, growth can be rapid and destructive. The radiographic aspect of a myxoma is that of a uni or multilocular, radiolucent lesion reminiscent of honeycomb or soap bubbles, depending on its size. It is an expansive tumor that may cause displacement or resorption of the teeth involved. Microscopically, the tumor is composed of round and spindle cells, with a star arrangement, arranged in a loose abundant myxoid stroma, containing only a few collagen fibrils. The treatment of choice is radical surgical excision because myxomas are not encapsulated and tend to infiltrate the surrounding bone. However, small tumors can be treated by curettage. Periodic reassessment is required for at least five years due to the high rate of recurrence. Larger tumors may need to be treated using a more extensive resection with a safety margin. This study reports a clinical case of odontogenic myxoma in a child aged 7 years. The tumor was located in the posterior region of the mandible and was surgically treated with an en bloc resection with preservation of the base of the mandible. The follow-up of the case is ongoing and no recurrence has been observed to date.
Subject(s)
Humans , Male , Female , Child , Pathology , Odontogenic TumorsABSTRACT
O Stryphnodendron barbadetiman (Barbatimão) é uma planta medicinal, uma leguminosa nativa do cerrado brasileiro, que tem como principal princípio ativo o tanino e que, na medicina popular, dentre outras indicações terapêuticas, destaca-se como cicatrizante. O controle do edema no processo de cicatrização é altamente benéfico, pois favorece a formação da crosta e a inibição de exsudatos. Este trabalho busca demonstrar se a solução de Barbatimão a 1 por cento apresenta, especificamente, uma ação antiedematosa. Para isto, foi realizado um estudo experimental comparativo entre a solução de Barbatimão a 1 por cento, a Clorhexidina a 0,12 por cento e um Grupo-controle, utilizando 89 ratos, que foram incisados na pele e, duas vezes ao dia, receberam a aplicação das soluções em testes sobre estas incisões. Depois, através da análise histológica dos tecidos foi verificada essa ação antiedematosa. A amostra foi dividida em 3 (três) grupos; o Grupo-controle, no qual nenhuma solução foi administrada; o grupo da solução de Barbatimão a 1 por cento e o grupo de Clorhexidina a 0,12 por cento. Os ratos foram sacrificados no 3°, 7° e 10° dias e foi realizado o exame histológico do tecido para identificação e mensuração do edema. Os resultados evidenciaram a ação antiedematosa da solução de Barbatimão a 1 por cento, confirmada pelas análises estatísticas com nível de significância de 0,014, como sendo maior que a Clorhexidina a 0,012 por cento (um índice de 37,07 por cento maior) e mais ainda do que o Grupo-controle (um índice de 45,11 por cento maior), notadamente nos primeiros dias de aplicações, o que é da maior importância clínica terapêutica
Subject(s)
Animals , Male , Rats , Wound Healing , Chlorhexidine , Edema/therapy , Stryphnodendron barbatimam , PhytotherapyABSTRACT
A group of youngsters (4-18 years old) in northeast Brazil was studied to stablish the prevalence of anaemia and intestinal parasitism, as well as to analyse the correlation between them. Two criteria were used to determine the state of anaemia, the level of haemoglobin and the mean of corpuscular volume. The first was considered a single criterion and the second an associated criteria, used in an attempt to correlate anaemia with iron deficiency. The prevalence of intestinal parasitism was 93 per cent while the prevalence of anaemia was 43.1 per cent and 16.1 per cent according to the criteria employed (single or associated respectively). Anaemia was significantly associated with both sex and age. No significant statistical difference was observed when the association was made between each parasite and anaemia even with those more related to anaemia.
Subject(s)
Humans , Child , Adolescent , Anemia/ethnology , Helminthiasis/ethnology , Brazil/ethnology , Intestinal Diseases, Parasitic/ethnologyABSTRACT
The epithelial cells of Panstrongylus megistus male accessory glands (MAG) present ultrastructural characteristics of a secretory cell. Their secretory products are accumulated in the lumen of the four MAG lobes. During the first 8 days of adult life a strong secretion activity occurs, accumulating enough material to produce the first spermatophore. Cerebral neurosecretions as well as juvenile hormone are both involved in MAG secretory activity regulation. Juvenile hormone seems to be the responsible for the stimulation of most protein synthesis in male accessory glands. Cerebral neurosecretion seems to be necessary to stimulate juvenile hormone production and release by the corpus allatum. Furthermore, neurosecretion is required for some polypeptides synthesis by MAG. Although topic application of precocene II to adult males does not reproduce the same effects on MAG as does allatectomy, this compound causes strong reduction on male reproductive capacity.