ABSTRACT
Introdução: O cuidado paliativo é uma das formas de tratamento do câncer avançado que objetiva o controle dos sintomas, conforto e a melhora da qualidade de vida dos pacientes e de seusfamiliares. Como membro da equipe multiprofissional, que atua neste âmbito, está o nutricionista,que exerce papel substancial nesses cuidados. Objetivo: Caracterizar a associação entre a atuaçãodo nutricionista e a qualidade de vida de pacientes oncológicos em cuidados paliativos. Material eMétodos: Foi realizada uma revisão bibliográfica integrativa com base no banco de dados Bireme,PubMed, Web of Science, Scopus e Cinahl e Embase, contemplando artigos publicados no períodode 2012 a 2017. Para composição da estratégia de busca foram utilizadas as palavras-chave:nutricionista; cuidados paliativos e câncer em português e inglês. Resultados: Foram encontrados187 artigos e excluídos 183 trabalhos, após leitura dos títulos, resumos e textos por não fazeremreferência ao tema proposto e aos critérios de inclusão. Foram inseridos um total de quatro estudos,sendo dois artigos da base Bireme, um artigo da base Web of Science e um da PubMed. Conclusão:O profissional nutricionista executa papel primordial nos cuidados paliativos, pois a terapianutricional colabora para a redução dos efeitos colaterais ocasionados pelo tratamento, realizandoorientações nutricionais pertinentes a estes indivíduos, além de fazer relação de vínculo entre aequipe, o paciente e seus familiares no tocante à alimentação, contribuindo assim para a melhora daqualidade de vida destes pacientes
Introduction: Palliative care is an alternative to treat cancer in its advanced stage. Treatment aims to control symptoms, comfort, and improve the quality of life of patients and their families. The nutritionist is a member of the multidisciplinary team who plays a substantial role in this care. Objective: Characterize the association between the nutritionist's professional practice and the quality of life of cancer patients in palliative care. Material and Methods: We conducted an integrative review of published literature from 2012 through 2017. Database searched included PubMed, Web of Science, Scopus, Cinahl, and Embase. The following keywords were used separately and combined in all databases and search engines: search terms, "nutritionist", "palliative care", and "cancer". The search was limited to Portuguese and English languages. Results: The integrative literature search resulted in the identification of 187 articles; of which 183 were excluded. Articles were first screened by review of the title. Selected articles were further screened by review of the abstract. The final chosen articles were read and the desired data summarized. Studies were excluded if they did not specifically record the proposed theme. Four studies were identified, two from Bireme, one from the Web of Science, and one from PubMed searches. Conclusion: Nutritionist's professional practice is primordial in the care of the patient. He/she helps to establish the best therapeutic plan, including nutrition therapy, in order to reduce the anxiety and suffering so peculiar in this approach. He/she also helps to reduce side effects caused by the treatment, making pertinent nutritional orientations/counseling to the individuals. The professional can establish a relationship between the team, the patient, and their families regarding nutrition. Thus, this professional might contribute to the improvement of patents' quality of life.
Subject(s)
Palliative Care/methods , Nutrition Therapy/methods , Nutritionists , Neoplasms/diet therapyABSTRACT
PURPOSE: To investigate nephrocalcinosis due to hyperoxaluria induced by two different inducing agents in rats. METHODS: Forty Sprague-Dawley male rats were randomly distributed into four groups: Group1 (Clinical control, n = 10); Group 2 (0.5% Ethylene Glycol + Vitamin D3, n = 10); Group 3 (1.25% Ethylene Glycol, n = 10); and Group 4 (5%Hydroxy L-proline, n = 10). Five animals from each group were euthanized after one week of follow-up (M1 Moment) and the remaining, after four weeks (M2 Moment). All animals underwent 24h urine dosages of calcium, oxalate, uric acid, citrate and serum creatinine. Histology and histomorphometric analyses were performed using Image J program in the hematoxylin-eosin stains. Calcium deposits in the renal parenchyma were quantified by PIXE technique (Proton Induced X-Ray Emission). RESULTS: 24h urinary parameters did not show any significant variations after 28 days of experiment except by hyperoxaluria that was significantly higher in Group 3. Histomorphometric analyses showed a significantly higher nephrocalcinosis in Group 2 (p<0.01). The calcium deposits in the renal parenchyma were 10 and 100 times higher in Group 2 in comparison to other groups in the M1 and M2 moments, respectively. CONCLUSION: The Group 2 (vitamin D3+Ethylene Glycol 0.5%) was the best model to induce nephrocalcinosis in rats after 28 days.