ABSTRACT
Objective To analyze the clinicopathological features of primary hyperthyroidism complicated with thyroid carcinoma. Methods From January 2010 to July 2018,418 patients complicated with thyroid cancer underwent thyroidectomy in the First Affiliated Hospital of Xiamen University were retrospectively analyzed.According to thyroid function,418 patients were divided into two group:A group ( n =39 ) had hyperthyroidism with thyroid carcinoma,and B group(n=379) had normal thyroid function.The clinicopathological features of the two groups were analyzed and compared.Results There were no statistically significant differences in age,sex,tumor stage and tumor diameter between the two groups(all P>0.05).The lymph node metastasis rate in A group was 17.9%(7/39), which was higher than that in B group[6.1%(23/379)] (χ2 =5.814,P=0.016).The incidence rate of temporary hypoparathyroidism in A group was 28.2%(11/39),which was higher than that in B group[13.2%(50/379)] (χ2 =6.394,P＜0.05).The local recurrence rate in A group was 5.1%(2/39),which was higher than that in B group[2.4%(9/379)],but there was no statistically significant difference(χ2 =0.248,P=0.619).The 5 -year disease-free survival rate in A group was 84. 6%( 33/39 ), which was lower than that in B group [ 95. 8%(363/379)]( χ2 =6.740,P＜0.05).Conclusion Hyperthyroidism complicated with thyroid carcinoma has high aggressive behavior and should be treated actively.
ABSTRACT
Objective@#To analyze the clinicopathological features of primary hyperthyroidism complicated with thyroid carcinoma.@*Methods@#From January 2010 to July 2018, 418 patients complicated with thyroid cancer underwent thyroidectomy in the First Affiliated Hospital of Xiamen University were retrospectively analyzed.According to thyroid function, 418 patients were divided into two group: A group(n=39) had hyperthyroidism with thyroid carcinoma, and B group(n=379) had normal thyroid function.The clinicopathological features of the two groups were analyzed and compared.@*Results@#There were no statistically significant differences in age, sex, tumor stage and tumor diameter between the two groups(all P>0.05). The lymph node metastasis rate in A group was 17.9%(7/39), which was higher than that in B group[6.1%(23/379)](χ2=5.814, P=0.016). The incidence rate of temporary hypoparathyroidism in A group was 28.2%(11/39), which was higher than that in B group[13.2%(50/379)](χ2=6.394, P<0.05). The local recurrence rate in A group was 5.1%(2/39), which was higher than that in B group[2.4%(9/379)], but there was no statistically significant difference(χ2=0.248, P=0.619). The 5-year disease-free survival rate in A group was 84.6%(33/39), which was lower than that in B group [95.8%(363/379)](χ2=6.740, P<0.05).@*Conclusion@#Hyperthyroidism complicated with thyroid carcinoma has high aggressive behavior and should be treated actively.
ABSTRACT
Objective To discuss the clinical characteristics of benign paroxysmal vertigo of childhood (BPVC) with frequent episodes,in order to further improve the level of diagnosis and treatment.Methods The clinical data of 25 cases with frequent episodes of BPVC were analyzed retrospectively.All cases were treated with regimen for migraine.Results Aspirin combined with propranolol had the best effect,quick effect,short period of treatment and minimal side effect.Conclusion Aspirin and propranolol are commonly used drugs in the treatment of migraine,which can effectively treat frequent episodes of BPVC,and is economical and practical,and it is conducive to promotion at the grass-roots level.It also confirms the homology of children with benign paroxysmal vertigo and migraine.