ABSTRACT
Angiomatoid malignant fibrous histiocytoma (MFH), is a rare but distinct fibrohistiocytic tumour of children and young adults, simulating a vascular neoplasm. A case of angiomatoid malignant fibrous histiocytoma in a 12 year old male is reported.
Subject(s)
Child , Histiocytoma, Benign Fibrous/pathology , Humans , Male , Scalp/pathology , Skin Neoplasms/pathologyABSTRACT
20 cases of Xanthogranulomatous Pyelonephritis (XPN) were encountered over an 8 year period, constituting 0.4 percent of the total of 47,370 surgical biopsies, 10 percent of the total of 188 nephrectomy specimens removed for various reasons and 35 percent of the nephrectomy specimens associated with chronic pyelonephritis. This is the largest single series, reported in Indian literature. 16 patients were adults and 4 were children, thus 25 percent of our cases were children, a significantly high proportion. Our youngest patient a 5 1/2 month old male, is to the best of our knowledge, the youngest case reported from India. Males predominated in our series, the M:F ratio being 3:1, this contrasts with western literature in which there is a definite female preponderance. The common presenting symptoms were lumbar pain, fever and palpable non-functioning kidney. 4 cases were complicated by cutaneous sinuses. There was a slight predominance of affectation of the left side over the right side. On gross examination, diffuse lesions were commoner than focal lesions and were seen in children as well. An accurate pre-operative diagnosis was made in only 2 cases, in the rest, the diagnosis was either tuberculosis or pyonephrosis. Thus XPN is quite frequently seen in the adult Indian population and is not as rare in children, as it was once thought to be.
Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , India/epidemiology , Infant , Male , Middle Aged , Prospective Studies , Pyelonephritis, Xanthogranulomatous/epidemiology , Retrospective StudiesABSTRACT
This paper presents an analysis of data collected from 242 cases of acute and chronic leukemia observed during a 10-year period. The incidence of childhood leukemia was 26.45%. In the present series, it was 35.95% for ALL, 21.9% AML, 38.4% CML and 2.89% CLL. The incidences of ALL and CML were found comparable to other series from Bombay. The geographical variations in the pattern of leukemias as observed in India are discussed.