ABSTRACT
Introduction: Gallbladder stone disease is common and aleading cause of inpatient admissions for gastro-intestinalproblem in modern world. Metabolic syndrome is slowlyassuming shape of a global epidemic. There is currently onlyminimal data regarding the relationship between cholelithiasisand Metabolic syndrome in Indians. This study aims to assessif there is an association between the presence of gallstonesand Metabolic Syndrome.Material and methods: At a tertiary care centre in Mumbai,100 patients with cholelithiasis were compared with 100controls to assess the profile with respect to MetabolicSyndrome.Result: 36% cases had Metabolic syndrome as against 16%controls. Of the components of Metabolic syndrome, obesitywas the only one found to have a positive association.Conclusion: In our study, gallstone disease showed astatistically significant association with metabolic syndrome,however this association was positive only in female patients.