Dynamic changes in the total fatty acids of diabetics during glucose challenge

Simultaneous determinations of blood glucose and total fatty acids were done in 20 diabetics and 20 non-diabetic Filipino patients undergoing glucose loading tests. The objective was to explore the interrelationship of glucose and fatty acids metabolism in the hope of establishing an explanation of the observation that Filipino diabetics in general are less prone to ketosis. Compared to foreign studies, this study disclosed a significantly different response of Filipino diabetics to the stress of induced hyperglycemia, i.e. high level of fasting FA. with delayed but sustained depression. The concomittant determination of the glucose tolerance curve and the F.A. profile aids in prognosticating the kelotic-prone diabetics