ABSTRACT
Background & objectives: Sexual functioning is a strong determinant of quality of life. Sexual dysfunction has been widely reported due to depressive disorder as well as selective serotonin reuptake inhibitors. Thus, treatment with antidepressants can culminate in a double-edged sword, leading to drug discontinuation and symptom relapse. The objective of this study was to assess the sexual functioning of sexually active females with depression, currently in remission, receiving escitalopram and to compare with healthy controls. Methods: Fifty female patients with depression, currently in remission, with self-reported normal pre-morbid sexual function and receiving escitalopram for at least three months, were assessed on female sexual function index (FSFI) questionnaire and compared with healthy controls. Results: Half of the patients (n=25, 50%) in group A were found to have sexual dysfunction (FSFI score <26.55), while, 90 per cent (n=45) had decreased desire, 86 per cent (n=43) had decreased arousal, 54 per cent (n=27) had decreased lubrication, 68 per cent (n=34) had decreased orgasm, 62 per cent (n=31) had decreased satisfaction and 32 per cent (n=16) had pain during sexual activity. Patients receiving escitalopram had significantly higher sexual dysfunction as compared to healthy controls in mean total FSFI score (P < 0.001) and all mean domain scores of FSFI except pain. Interpretation & conclusions: A significant proportion of sexually active females with depression currently in remission, receiving escitalopram, reported dysfunction in all domains of sexual function; thus, routine screening for sexual dysfunction during follow up is advisable for early identification and prompt treatment.
ABSTRACT
Background and Objectives: Family accommodation (FA) refers to ways in which family members assistthe patient in the performance of rituals, compulsions, avoidance of anxiety provoking situations, ormodification of daily routines to assist a relative with obsessive-compulsive disorder. The purpose of thisstudy was to study the association between the family accommodation and dimensions of obsessivecompulsive disorder (OCD).Methods: The study was included 45patients and their family members, Yale brown Obsessive-Compulsivescale (YBOCS) was used to assess the severity of OCD in patients and Dimensional Yale brown ObsessiveCompulsive scale (DYBOCS) was used to identify the severity of different dimensions in OCD patientsfamily members were assessed on Family Accommodation Scale for Obsessive–Compulsive Disorder – SelfRated version (FAS-SR) for understanding accommodation level in family. A Pearson’s correlationcoefficient was used to evaluate the association between variables.Results: FA was found to be highly present in the family of patients with OCD. On the DYBOCS we foundthe dimension of cleaning and washing were prevalent and highly correlated with FA.Conclusion: The findings suggested that the family accommodation is very common in families of OCDpatients and strongly associated with symptom severity of few specific dimensions.