ABSTRACT
Objective To guide proper clinical medication through analysing the main pathogen and the drug resistant situation of suppurative otitis media of the local children .Methods Making the bacterial culture and antibiotic susceptibility tests with the ear secretion collected randomly of 133 children with suppurative otitis media .Results Among the 133 cases ,110 pathogenic germs were separated totally ,as the detectable rate was 98 .23% ,and Among them ,56 streptococcus pneumoniae ,26 staphylococcus au‐reus (3 multi‐drug resistant to oxacillin) ,11 streptococcus pyogenes ,4 Haemophilus influenza and 13 others .Streptococcus pneu‐moniae was susceptible of ceftriaxoneo ,cefotaxime ,chloramphenicol ,levofloxacin ,quinupristin/dalfopristin and vancomycin ,while was resistant to clindamycin ,tetracycline ,sulfamethoxazole and erythromycin .11 .54% of the total detectable rate of MRSA in Staphylococcus aureus ,produce to β‐ lactamase detection rate was 84 .61% .Streptococcus pyogenes had a high resistance rate to erythrocin ,while a low rate to the other antimicrobial .Conclusion The main pathogen of the local children suppurative otitis media are Streptococcus pneumonia ,Staphylococcus aureus and Streptococcus pyogenes .The clinicians should use antibiotics reasonably according to the antimicrobial susceptibility results .
ABSTRACT
Objective To analyze the distribution of common pathogenic bacteria and their drug resistance ,in children with bron‐chial pneumonia ,and provide reference for making antimicrobial treatment strategies .Methods 857 hospitalized pediatric patients with bronchopneumonia from January to December 2014 were enrolled in the study ,bacterial culture and drug susceptibility test were performed ,and the results were analyzed .Results In the 857 pdiatric patients ,the positive rate was 36 .87% (316/857) .A‐mong them ,175 cases were gram positive bacteria(20 .42% ) ,141 cases were gram negative bacteria(16 .45% ) ,140 cases were Streptococcus pneumoniae(16 .34% ) ,70 cases were Haemophilus influenzae(8 .17% ) .The susceptibility of Streptococcus pneu‐moniae to penicillin with enzyme inhibitors ,levofloxacin and vancomycin was the highest(higher than 90 .00% ) ,followed by the third generation cephalosporin(non meningitis) ,to which the sensitivity rate were above 80 .00% .The susceptibility of Haemophi‐lus influenzae to the third generation cephalosporins ,ampicillin/Sulbactam ,levofloxacin and imipenem were the highest(more than 90 .00% ) ,while the resistance to ampicillin and cotrimoxazole was 80 .00% .Conclusion Gram positive bacteria are the most im‐portant pathogenic bacteria ,and Streptococcus pneumoniae is the most common bacteria in bronchopneumonia .In clinical treatment , the results of drug sensitivity test should be paid attention to ,so as to adjust the treatment plan and achieve the ideal effect .