ABSTRACT
Background: The measurement of color Doppler ultrasonographic indices, such as resistive index [RI] can help in the evaluation of a transplanted kidney. This study sought to examine correlation between color Doppler ultrasonographic indices and serum creatinine levels before and after renal transplantation
Methods: A total of 100 patients with end stage renal disease undergoing kidney transplantation were enrolled in this study. Serum creatinine levels was measured before transplantation, on day 5 and at the end of the third month after transplantation. Central and peripheral RI values of the transplanted kidney were also documented on day 5 an month 3 posttransplantation
Results: Creatinine level at the end of third month had positive correlation with central [r=0.27 and p=0.007] and peripheral RI values [r=0.26 and p=0.009] in day 5 after transplantation. There was also a significant positive correlation between the serum level of creatinine at the end of the third month and central [r=0.50 and p<0.001] and peripheral RI values [r=0.50 and p<0.001] at the third month posttransplantation. At an optimal cut-off point of 0.51 for the central RI on fifth day, the sensitivity, specificity, positive predictive value, and negative predictive value for predicting a malfunctioning transplanted kidney were 93%, 30%, 76%, and 64%, respectively. The corresponding values of the peripheral RI on fifth day were 43%, 67%, 75%, and 33%, respectively using an optimal cut-off point equivalent to 0.70
Conclusions: Both peripheral and central RI values on day 5 can be used for predicting malfunctioning transplanted kidney
ABSTRACT
Background: Peritoneal cytology has received little attention in the literature, but it may be an additional useful means in evaluating patients with primary gastric cancer. The aim of this study was to examine the diagnostic accuracy of peritoneal fluid lavage cytology in detecting peritoneal seeding in patients with gastric adenocarcinoma
Methods: A total of 50 patients with gastric adenocarcinoma who were candidates for laparotomy based on the findings of computed tomographic examination were recruited. Diagnostic peritoneal lavage [DPL] was performed just before laparotomy and the peritoneal lavage fluid was sent for cytological examination for presence or absence of malignant cells. Findings in terms of peritoneal involvement during laparotomy were regarded as the standard results
Results: DPL cytology was positive for the presence of malignant cells in the peritoneal fluid in 25 cases [50%]. According to the intraoperative findings 22 patients [44%] had peritoneal metastatic disease, whereas in 28 patients [56%] no gross indicator of metastasis was detected. The sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of cytology in detecting peritoneal seeding were 59%, 57%, 52%, 64%, 1.38 and 1.40, respectively. The agreement between cytology and diagnostic laparotomy was 58%
Conclusion: According to the findings of the present study peritoneal lavage solely is not a proper diagnostic method for early recognition of resectable/nonresectable gastric cancers