ABSTRACT
Objective To investigate the clinical effect of posterior short-segment pedicle screw reduction and fixation without fusion in treatment of thoracolumbar mono-segmental compression fractures.Methods Thirty cases of thoracolumbar mono-segmental compression fractures admitted from January 2009 to February 2010 were assigned to single posterior pedicle screw fixation (screw group,n =15) and posterior pedicle screw fixation with posterolateral fusion (fusion group,n =15) according to random number table.Clinical results in the two groups were assessed based on Cobb' s angle,anterior vertebral body height ratio (％) and Oswestry disability index (ODI) before operation,after operation,prior to the removal of implant and at the latest follow-up.Results All the cases were followed up for average 24 months.Both operation time and blood loss were less in screw group than in fusion group [(76.58 ±12.67) min vs (116.29 ± 17.45) min,P ＜ 0.01 ; (287.54 ± 30.76) ml vs (480.34 ± 100.54) ml,P ＜0.01],whereas there were no statistical differences between the two groups in aspects of Cobb' s angle and anterior vertebral body height ratio before and after operation,prior to the removal of implant as well as at the latest follow-up.Moreover,no statistical difference of ODI was noted between the two groups prior to the removal of implant and at the latest follow-up.Conclusion Posterior pedicle screw fixation without bone grafting achieves similar effects with pedicle screw fixation with bone grafting.
ABSTRACT
OBJECTIVE： To survey an evaluate the current situation and trend of the use of digestive system drugs.METHODS： To make a survey of the use of the above-mentioned drugs in 51 hospitals of four provinces in southwest China during the period 1999～2000 in respect to the sum of money of sales， main kinds， DDDs etc.and to analyse the clinical application of these drugs.RESULTS： As the sum of money for sales of the digestive system drugs， it was increased 42.08％ in 2000 compared with that in 1999.As the DDDs of the digestive system drugs， it is increased 8.85％ in 2000 compared with that in 1999.The average cost of DDD was 2.76 yuan in 2000 and 2.60 yuan in 1999.CONCLUSION： The digestive system drugs is an important kind of drug which has prospects of fast increase.