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Objective@#To understand the infection status and genetic characteristics of Norovirus from foodborne diseases in sentinel hospital of Ma′anshan city.@*Methods@#The 911 stool samples and epidemiological data of the patients with foodborne disease were collected from three hospitals of Ma′anshan city during January 2015 to June 2018. The G Ⅰ and G Ⅱ Norovirus were detected by real-time reverse transcription PCR. Some of the positive specimens were amplified by conventional reverse transcription PCR, and the PCR products were sequenced for sequence alignment and phylogenetic analysis.@*Results@#The positive rate of Norovirus was 14.7% (134/911), in which 7 strains were G Ⅰ, 124 strains were G Ⅱ and 3 strains were mixed infection. Norovirus can be detected throughout the year, with high positive rate from December to April of the next year [24.4%(20/82)-45.3%(24/53)]. The 78 males (15.5%) and 55 females (13.7%) were positive for Norovirus (χ2=0.58,P=0.448). There was no significant difference in different age groups (χ2=9.55, P=0.089). A total of 79 strains were successfully sequenced, 4 strains were G Ⅰ group(5.1%), 75 strains were G Ⅱ group (94.9%). The predominant strains were GⅡ.17 and GⅡ.4, aud the number were 35 and 15 respectively. The predominant strains were different in different years. The main strain was GⅡ.17 in 2015 (30, 68.2%),GⅡ.4 in 2016 (5/9) and 2017 (8/16), but GⅡ.3 in 2018 (3/6).@*Conclusion@#Norovirus diarrhea was popular in Ma′anshan city throughout the year,especially in winter and spring. The prevalent strain was GⅡ,genotypes were diversified distribution,the dominant strains were GⅡ.17 and GⅡ.4. The predominant strains were different in different years.
ABSTRACT
Objective To investigate the therapy and treatment opportunities for spontaneous pneumothorax in the older adults.Methods Clinical data and therapy outcomes of 124 elderly patients with spontaneous pneumothorax were collected in our hospital.The treatment methods and operation opportunity were summarized.Results Among 124 elderly patients,2 cases (1.6％) were treated with oxygen and medicine conservative treatment.42 cases (33.9 ％) had good degree of postoperative atelectasis after closed drainage of pleural cavity,and no obvious symptoms of pneumothorax were found by thoracic CT.80 cases (64.5％) obtained well recovery after thoracoscope surgery,2 cases (1.6％) had recurrence during the 6-month follow-up and recovered after conservative treatment in hospital.Conclusions The closed drainage of thoracic cavity has a good curative effect on senile spontaneous pneumothorax,but it is easy to relapse.Thoracoscope surgery has definite clinical curative effect with less recurrence.The operation opportunities should be considered accurately in order to avoid the treatment delay.