ABSTRACT
Objective To study and establish the GC fingerprint of Rhizoma Ligustici from Suichuan to guide the standardization of planting Rhizoma Ligustici. MethodsTen batches of volatile oils were extracted by steam distillation, then separated by capillary gas chromatography and determined by GC/MS. ResultsThe similarity of ten batches of Rhizoma Ligustici from Suichuan is higher, all samples contain derivatives of phthalides and allyl-benzene. ConclusionThe method is reliable, accurate and can be used to evaluate the quality of Suichuan Rhizoma Ligustici and guide the planting.
ABSTRACT
XIAOZHONG ZHITONG GAO is a soft inunctum used with the anti inflammatory and analgesic effects
ABSTRACT
Objective To study the anti-arrhythmia effect of crocetin and corresponding mechanism.Methods Animals (rats or guinea pigs) were randomly and equally divided into five groups:saline control group,positive drug control group,low-dose,medium-dose and high-dose crocetin group.Animals were anesthetized with urethane (1.2g/kg),then followed by the perfusion of aconitine (10?g/mL) through caudal vein in rats,or of ouabain (9?g/mL) through external jugular vain in guinea pigs in a constant velocity of 0.1mL/min,and the emergence time of ventricular fibrillation (VF),ventricular extrasystole (VE),ventricular tachycanlia (VT) and cardiac arrest (CA) were then detected and recorded.The recorded time was then translated to the cumulated amount of aconitine and ouabain.Experimental arrhythmia was induced by rapid injection of 4% CaCl2 (140mg/kg),and the emergence time,persistence time,incidence and death of arrhythmia after the administration were observed.Results Compared with the animals in saline control group,obvious anti-arrhythmia effects of crocetin were observed in those animals in each of crocetin groups (P