ABSTRACT
China-made amrinone (AMR) was orally administered to 10 patients with chro- nic congestive heart failure(CHF) for 72 hours, its mitral valve blood flow spectral shift was observed by pulsed Doppier echocardiograp hy(PDE). We found that peak A decreased, and peak A/peak E ratio decreased significantly. It suggested that AMR could improve left ventricular diastolic function. Early diastolic drag acceleration increased, it is one index of left ventricular diastolic function, its elevation suggested that left ventricular diastolic function had some improvement. These observation suggested that AMR could improve left ventricular diastolic function for hypertensive heart disease, coronary artery disease, congestive cardiom-yopathy with limited left ventricular diastolic function